ID A0A1C5F5R8_9ACTN Unreviewed; 948 AA.
AC A0A1C5F5R8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:SCG02909.1};
GN ORFNames=GA0115259_108032 {ECO:0000313|EMBL:SCG02909.1};
OS Streptomyces sp. MnatMP-M17.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1839780 {ECO:0000313|EMBL:SCG02909.1, ECO:0000313|Proteomes:UP000198886};
RN [1] {ECO:0000313|EMBL:SCG02909.1, ECO:0000313|Proteomes:UP000198886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MnatMP-M17 {ECO:0000313|EMBL:SCG02909.1,
RC ECO:0000313|Proteomes:UP000198886};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; FMDK01000757; SCG02909.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5F5R8; -.
DR Proteomes; UP000198886; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000198886};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 853..886
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 245..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..282
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 103237 MW; 60BDBF8FFDD37F64 CRC64;
MGLPVEFGLL GSIEARLDGR PVELGHARQR CVLAALMADA NRLVSVDQLI DRVWGERPPQ
RAQASLYSYI SRLRQALSPA AGDADIERRS GGYVLTVDTS AVDLHRFREL VERARTADDS
EAEALFEEAL ALWRGDAATE QDSPWFNSLR EALRRERHAA ELDLVDIRLR SGRHTGLPAE
LATRVEAHPL DERLVGQLML ALYRGGRPAD ALARYEEIRQ RLATELGTDP GPPLRELRQR
ILTADPVLDK PAPVRRTPGS SGSPVEPAAP PAPVPRQLPA PPPMFTGRSR ELARLGKLLE
PRAERGGTVV ISAIGGTGGI GKTWLALRWA HSRQERFPDG QLYADLRGFS PSGEPVPAAV
VVRAFLEALG APPGTIPADP DAQAALYRSL TAGKRLLILL DNARSTTQVL PLLPGSPTCT
VLVTSRHQLT GLTAAHGGTP LTLDVLTDTE ALELLTRHLG AARIAAEPDA AATLLKHCAG
LPLAISILAA RATMNPALSL AALASELHEA ATRLDALDAG ETATDLRAVF ASSYEALDAP
TARVFRLLSL APGADIGLPA AASLTGLPLS RLRAHLRTLH SAHLVQEHTP HRYTCHDLLR
AYATELAQSF DTEAERTAAL DRLLDHYVHT AFAADRLLLP HRDPLTLPPP ADGLTPERLA
DHDEAMKWFS REHTVLTAAV EHAARLGLDA RVWQLAWATL TFQSRLGHWH EVESAQRAAL
AAAVRLGDRS AQAECRRGLA WALSQTARVD EARDELEVAL ALSRDLGDDP GRAHAHLTLS
WLCELEGDER AAYEHDLTAL DLFTSSSHRS GRARALNALG WDRIQRGDYQ QAVLDCEEAL
ALQQELDDER GQAGTWDTLG YAYQRIGDHG NAKECFRHSL RLNRALGHRF NEAETLIHLG
ETHRATGALP AAREAWQQAL TVLIGIGHPE TELDRVRTML QELNTPTN
//
