ID A0A1C5GLD9_9ACTN Unreviewed; 321 AA.
AC A0A1C5GLD9;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=RNA polymerase sigma-70 factor, ECF subfamily {ECO:0000313|EMBL:SCG34606.1};
GN ORFNames=GA0074704_0096 {ECO:0000313|EMBL:SCG34606.1};
OS Micromonospora siamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=299152 {ECO:0000313|EMBL:SCG34606.1, ECO:0000313|Proteomes:UP000198210};
RN [1] {ECO:0000313|EMBL:SCG34606.1, ECO:0000313|Proteomes:UP000198210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45097 {ECO:0000313|EMBL:SCG34606.1,
RC ECO:0000313|Proteomes:UP000198210};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
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DR EMBL; LT607751; SCG34606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5GLD9; -.
DR Proteomes; UP000198210; Chromosome i.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR037401; SnoaL-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30173:SF43; ECF RNA POLYMERASE SIGMA FACTOR SIGI-RELATED; 1.
DR PANTHER; PTHR30173; SIGMA 19 FACTOR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR Pfam; PF12680; SnoaL_2; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000198210};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..78
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 121..171
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
FT DOMAIN 192..294
FT /note="SnoaL-like"
FT /evidence="ECO:0000259|Pfam:PF12680"
SQ SEQUENCE 321 AA; 34811 MW; 501AD4FB3B9BA06E CRC64;
MTVETTTAEF EAERGRLTAV AYRMLGSRGE AEDAVQETWL RYAAALGDPA ARAEVRHLRA
WLTTTCARIC LDVLRSARVR RETYPGQWLP EPLVAPLPPA ADGFAPDPAE RALRRDQLGT
ALQVVLERLG PEQRVAFVLH DVFAVPFARI AEALDTTPEA ARQLASRARR AVTAPDVPRH
TADPAEQRRV LAAFLAATES GDLTALVRVL APDVVLIGDS GGRFPAARRP VTGPDAVGRF
TLGLFAQAER RGQRVRSGVV LVDGSLGLQF EGVHTDGRPM RLVVAFAMAD GRITGIFNQL
NPDKVADLPA LPESAGWPPR W
//
