ID A0A1C5GPD4_9ACTN Unreviewed; 846 AA.
AC A0A1C5GPD4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC {ECO:0000313|EMBL:SCG35437.1};
GN ORFNames=GA0074704_0223 {ECO:0000313|EMBL:SCG35437.1};
OS Micromonospora siamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=299152 {ECO:0000313|EMBL:SCG35437.1, ECO:0000313|Proteomes:UP000198210};
RN [1] {ECO:0000313|EMBL:SCG35437.1, ECO:0000313|Proteomes:UP000198210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45097 {ECO:0000313|EMBL:SCG35437.1,
RC ECO:0000313|Proteomes:UP000198210};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT607751; SCG35437.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5GPD4; -.
DR Proteomes; UP000198210; Chromosome i.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS50151; UVR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SCG35437.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Hydrolase {ECO:0000313|EMBL:SCG35437.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:SCG35437.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198210};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 422..457
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 826..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 846 AA; 93801 MW; C7466E919279DA32 CRC64;
MFERFTDRAR RVVVLAQEEA RMLNHNYIGT EHILLGLIHE GEGVAAKALE SLGISLEGVR
QQVEEIIGQG QQAPSGHIPF TPRAKKVLEL SLREALQLGH NYIGTEHILL GLIREGEGVA
AQVLVKLGAD LNRVRQQVIQ LLSGYQGKEP AAAGAAPGEA APSTSLVLDQ FGRNLTQAAR
EGKLDPVIGR EKEIERVMQV LSRRTKNNPV LIGEPGVGKT AVVEGLSQKI IKGEVPETLK
DKQLYTLDLG ALVAGSRYRG DFEERLKKVL KEIRTRGDII LFIDEIHTLV GAGAAEGAID
AASILKPMLA RGELQTIGAT TLDEYRKHLE KDAALERRFQ PIQVGEPSLA HTIEILKGLR
DRYEAHHRVS ITDAALVAAA TLADRYISDR FLPDKAIDLI DEAGARMRIR RMTAPPDLRD
FDERIAQVRK DKESAIDAQD FERAAQLRDK EKQLLGQKAQ REKEWKAGDL DVVSEVDDEQ
IAEVLGNWTG IPVYKLTEEE TSRLLRMEDE LHKRVIGQED AVKAVSKAIR RTRAGLKDPK
RPSGSFIFAG PSGVGKTELS KALAEFLFGS EDALIQLDMS EFHDRYTVSR LVGAPPGYVG
YDEGGQLTEK VRRRPFSVVL FDEIEKAHPD VFNTLLQILE DGRLTDGQGR IVDFKNTVII
LTTNLGTRDV AKAVSLGFQA SEDSESNYDR MKQKVNDELK QHFRPEFLNR IDDTIVFHQL
RQSEILSIVD IMIQRIETQL RNKDMGLELT DNAKKYLAKK GFDPVLGARP LRRTIQRDIE
DNLSERILFN ELTPGQIVVV DCEGDPEDID KSKLVFRGAE KPVDVPDAVP ADLGGTAATG
ADDAAA
//
