ID A0A1C5GZQ5_9ACTN Unreviewed; 193 AA.
AC A0A1C5GZQ5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=nicotinamidase {ECO:0000256|ARBA:ARBA00039017};
DE EC=3.5.1.19 {ECO:0000256|ARBA:ARBA00039017};
DE AltName: Full=Nicotinamide deamidase {ECO:0000256|ARBA:ARBA00043224};
GN ORFNames=GA0070613_0604 {ECO:0000313|EMBL:SCG39087.1};
OS Micromonospora inositola.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47865 {ECO:0000313|EMBL:SCG39087.1, ECO:0000313|Proteomes:UP000198221};
RN [1] {ECO:0000313|EMBL:SCG39087.1, ECO:0000313|Proteomes:UP000198221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43819 {ECO:0000313|EMBL:SCG39087.1,
RC ECO:0000313|Proteomes:UP000198221};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; nicotinate biosynthesis; nicotinate
CC from nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00037900}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; LT607754; SCG39087.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5GZQ5; -.
DR OrthoDB; 9791276at2; -.
DR Proteomes; UP000198221; Chromosome i.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR11080:SF2; LD05707P; 1.
DR PANTHER; PTHR11080; PYRAZINAMIDASE/NICOTINAMIDASE; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Reference proteome {ECO:0000313|Proteomes:UP000198221}.
FT DOMAIN 4..184
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 193 AA; 20327 MW; 5A3AE95423D6E6C5 CRC64;
MANALIIVDV QNDFCEGGSL AVAGGADVAA GISRLLAAEP DRWDHLVATK DYHVDPGEHF
GDPPDYVDSW PRHCVVGTAG SEFHPNLETG RVEAIFHKGE HAAAYSGFEG HAGDGECLAD
WLRARRVDRV DLVGIATDHC VRATALDAAR EGFGTTVLLD LTAAVAPMTL DVALRAMDGA
GVTMLGEPVI RAA
//
