ID   A0A1C5H2F5_9ACTN        Unreviewed;       305 AA.
AC   A0A1C5H2F5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Cobalt-zinc-cadmium efflux system protein {ECO:0000313|EMBL:SCG40027.1};
GN   ORFNames=GA0070609_0808 {ECO:0000313|EMBL:SCG40027.1};
OS   Micromonospora echinaurantiaca.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=47857 {ECO:0000313|EMBL:SCG40027.1, ECO:0000313|Proteomes:UP000198217};
RN   [1] {ECO:0000313|EMBL:SCG40027.1, ECO:0000313|Proteomes:UP000198217}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43904 {ECO:0000313|EMBL:SCG40027.1,
RC   ECO:0000313|Proteomes:UP000198217};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; LT607750; SCG40027.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C5H2F5; -.
DR   Proteomes; UP000198217; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR   InterPro; IPR002524; Cation_efflux.
DR   InterPro; IPR036837; Cation_efflux_CTD_sf.
DR   InterPro; IPR027469; Cation_efflux_TMD_sf.
DR   NCBIfam; TIGR01297; CDF; 1.
DR   PANTHER; PTHR11562; CATION EFFLUX PROTEIN/ ZINC TRANSPORTER; 1.
DR   PANTHER; PTHR11562:SF17; LD05335P; 1.
DR   Pfam; PF01545; Cation_efflux; 1.
DR   SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR   SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198217};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        23..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        122..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   305 AA;  31877 MW;  C0416F95A7ADCB3E CRC64;
     MGAGHDHHHG SAVNAAHHHR GRLWAAFGLL TALMVVEAVA AFRTGSLALL SDAGHMFTDV
     LGIGMALAAI TATRRTTGDP QRTFGLYRLE VLAALANAVL LSGVAVYVVI EAVRRFGDPP
     EVLAGPMLVV ALLGLLANVA AFALLRSGAR ESINVRGAYL EVLGDLLGSL GVIGAALLIA
     VTDWWWADPL VAVGIGLFIL PRTWRLGRAA LRILVQAAPE HLQVTAVHDR LAAVPGVAGV
     HDLHVWTLTS GMEVASAHLT MAPGADVGRV LAAARTALHE DFRIEHATLQ IEPGAAPGAC
     GSVEW
//