ID   A0A1C5H307_9ACTN        Unreviewed;       510 AA.
AC   A0A1C5H307;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=NADH dehydrogenase subunit M {ECO:0000313|EMBL:SCG40425.1};
GN   ORFNames=GA0074704_0975 {ECO:0000313|EMBL:SCG40425.1};
OS   Micromonospora siamensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=299152 {ECO:0000313|EMBL:SCG40425.1, ECO:0000313|Proteomes:UP000198210};
RN   [1] {ECO:0000313|EMBL:SCG40425.1, ECO:0000313|Proteomes:UP000198210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45097 {ECO:0000313|EMBL:SCG40425.1,
RC   ECO:0000313|Proteomes:UP000198210};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC       {ECO:0000256|ARBA:ARBA00009025}.
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DR   EMBL; LT607751; SCG40425.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C5H307; -.
DR   Proteomes; UP000198210; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   NCBIfam; TIGR01972; NDH_I_M; 1.
DR   PANTHER; PTHR43507:SF1; NAD(P)H-QUINONE OXIDOREDUCTASE CHAIN 4, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198210};
KW   Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        77..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        114..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        170..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        241..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        332..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        459..475
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          134..421
FT                   /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT                   subunit"
FT                   /evidence="ECO:0000259|Pfam:PF00361"
SQ   SEQUENCE   510 AA;  55050 MW;  1E2342E40B4955D5 CRC64;
     MSNFPFLSVL TVAPLVGALV VALLPRRNPE LAKQVAFGWS LLVLVLSVIM WITFQAGGDR
     FQFRESYPWI PTWGVRFTFA ADGIALVMLM LIAILVPLVI LASWHDAESS KRSVPVYFAL
     LLILESTMIG VFAAADVFLF YVFFEVMLVP MYFLIGSYGG HQRQYAAVKF FLYSLVGGLF
     MLAAVIGLWV VGGRTFDWNQ LVDADIATGT ARWLFLGFFL AFAIKAPFFP FHTWLPDAGR
     AAPAGAAALL VGVLDKVGTF GILRYCLPLF PEAAKWFAPW ALALGLIGII YAALLAVGQN
     DLKRLVSYTS IAHFGFIGVG IFAFTTQAGT GAVLYMLNHG LATGLLFLVV GMLIARRGSA
     MISDFGGAGK LVPLLAGVLF FAGLASLALP GTAPFISEFL VLIGTFTVNK PVAVIATLGI
     VLAAAYVLWM VQRTTQGTLN PALTEVDGMR RDLNLREKAV VAPLIVLIVL LGFYPKPVTD
     VINPAVQATM QDVGKTDPAP EVGTVQEARR
//