ID A0A1C5HCT9_9ACTN Unreviewed; 739 AA.
AC A0A1C5HCT9;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SCG43836.1};
GN ORFNames=GA0070613_1144 {ECO:0000313|EMBL:SCG43836.1};
OS Micromonospora inositola.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47865 {ECO:0000313|EMBL:SCG43836.1, ECO:0000313|Proteomes:UP000198221};
RN [1] {ECO:0000313|EMBL:SCG43836.1, ECO:0000313|Proteomes:UP000198221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43819 {ECO:0000313|EMBL:SCG43836.1,
RC ECO:0000313|Proteomes:UP000198221};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT607754; SCG43836.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5HCT9; -.
DR Proteomes; UP000198221; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198221}.
FT DOMAIN 263..315
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 550..688
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 444..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 683..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 739 AA; 75845 MW; 4CA997E30D30C1FB CRC64;
MTLRGRLTAA FLAVVLGPVL LGAFFVGSTM SAVDRGRSTE RLGLAAAGVR TSVDALCQQL
RAAADAVALV ADPAARPGAA TQVVGRGLAA AVRVTDTAGR TTYATPGGPA EPWQDCSGVP
RASGPVRALA ARVQLRDPTG ADLGTVVAAQ PVDPAFVARL AAVTGVAVTL LDDAAGPVRV
THTTENRAVR AAVLAAADRI DGDRVTATAD GRYVRRVGPA PGQPLPLVLS VPGERPPGLY
AALVGAVVLA ALLAVLAAGR LARVTTRPLV ELAGAVDRVA HGDLSTRVPV RTRDEIGRLA
LAFNRMTRET GTYVTALTSS RDQLRGHLAV LGDTLASTHD LHRILRVILH SAIAATGARA
GAVLLLDAGG VLVGQCAEGL EGRWAADDPT DAATLRVPVG VGVVGAVIAT GEPLRGRWEP
ATAATGEPLC ETYIAVPFAA PGAAELGGRG DPDRPGHPPA GGDGDGGAAG GGTLGVLALY
DRLGADEFDD DDLETLRTFA GHAAVAVDNV RVHEEAQRLS LTDPLTGLWN YRYLRESIRR
EVERANRFGR MLSVLALDLD RFKDVNDTWG HAAGDAVLVE FARRVRGEIR EVDLAFRHGG
EEFVVLLPET DARGAAIVAE RLGAVVRGSP VPVDGHSGEP VLVPVTVSIG IAVYPDHAAT
GQHVLDAADD ALYAAKAAGR DGYRVAQPPD PAPAQELPVV AGAVSPPDGQ PRAGAVDAAG
GGPSGASSGP HPPRQSRGR
//
