ID   A0A1C5HI05_9ACTN        Unreviewed;       358 AA.
AC   A0A1C5HI05;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=RNA polymerase, sigma subunit, ECF family {ECO:0000313|EMBL:SCG45563.1};
GN   ORFNames=GA0074704_1757 {ECO:0000313|EMBL:SCG45563.1};
OS   Micromonospora siamensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=299152 {ECO:0000313|EMBL:SCG45563.1, ECO:0000313|Proteomes:UP000198210};
RN   [1] {ECO:0000313|EMBL:SCG45563.1, ECO:0000313|Proteomes:UP000198210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45097 {ECO:0000313|EMBL:SCG45563.1,
RC   ECO:0000313|Proteomes:UP000198210};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC       formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC       omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC       transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
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DR   EMBL; LT607751; SCG45563.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C5HI05; -.
DR   Proteomes; UP000198210; Chromosome i.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 3.10.450.50; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014305; RNA_pol_sigma-G_actinobac.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR037401; SnoaL-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   NCBIfam; TIGR02960; SigX5; 1.
DR   PANTHER; PTHR43133:SF46; ECF RNA POLYMERASE SIGMA FACTOR SIGG; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   Pfam; PF12680; SnoaL_2; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198210};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          13..81
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          135..187
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
FT   DOMAIN          209..304
FT                   /note="SnoaL-like"
FT                   /evidence="ECO:0000259|Pfam:PF12680"
FT   REGION          85..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          326..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   358 AA;  39297 MW;  57719B383AFAF1FA CRC64;
     MSEVATSTSV EELLEPYRSE LTGYCYRMLG SAFEAEDAVQ DTFVRAWRSF ERFEGRSALR
     TWLYRIATNV CLSMLTSAQR RVRPMDLGPA ASGDATHPGE PRPDEIWTGP APDDRVLPER
     ADPAEVIAGR ESVRLAFVAA LQHLPPRQRA VLILREVLAW SAQEVAELLD TSVASVNSAL
     QRARATLAAA DTRGDVRRPL DDEQRALLAR YVRAFEAYDL TALAALLHED ATLSMPPMPL
     WLRGPRDITT WMAGTGRGCR GSRLVPVLAN GQPAFAQYRP DPDGPGHGAW ALVVLDISAG
     RITRLNYFLD TDRLFPLFGL PDRLEEGAGE AEQAGQLPQA GVAAVDHEPP AVPSRRQP
//