ID A0A1C5HQG3_9ACTN Unreviewed; 442 AA.
AC A0A1C5HQG3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Transmembrane secretion effector {ECO:0000313|EMBL:SCG48222.1};
GN ORFNames=GA0070609_2038 {ECO:0000313|EMBL:SCG48222.1};
OS Micromonospora echinaurantiaca.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47857 {ECO:0000313|EMBL:SCG48222.1, ECO:0000313|Proteomes:UP000198217};
RN [1] {ECO:0000313|EMBL:SCG48222.1, ECO:0000313|Proteomes:UP000198217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43904 {ECO:0000313|EMBL:SCG48222.1,
RC ECO:0000313|Proteomes:UP000198217};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LT607750; SCG48222.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5HQG3; -.
DR Proteomes; UP000198217; Chromosome i.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR23513:SF6; MULTIDRUG EFFLUX PUMP TAP; 1.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198217};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:SCG48222.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 412..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 45064 MW; 8C7DDC71A25EB750 CRC64;
MTRNAGESLG ARFAKLWAAS TMSALGSGLA TVAAPLFVAS RTDDPLVVAA ASGVAWLPWL
LFALPGGVLV DRVDRRRLMI VIDWVRVAAL AVLAAAIMTD RAGVALLYAV LFVVNTGEIV
FRAASQAMVP AVVPRDLLER ANGWLSGGSM LMHGMLAGPL GGFLFVLAAS SPFLANAVTY
ALSAVLLALI AGSYRAGPAS VGGATARSVR ADIDEGFRWL AGQRLLRTMT VLIGLLNLTL
TAAIAVLVLL AAERLHLGSV GYGALFTCMA VGGVLGAAVG DRLIARIGAT WTIRVGLLVE
AGLHLALAAS RSAAVVGFAL FAFGVHGALW NIVANSLRQR LTPTALQGRV GSTTLFIAAG
GNCLGALLGG AVAATFGLTV PYWIGFVVAV GVSAATWRVF DRATVARAYA APAPDQPAAP
APGQPAASDR PADEGAAASP VA
//
