ID A0A1C5HU75_9ACTN Unreviewed; 816 AA.
AC A0A1C5HU75;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=GtrA-like protein {ECO:0000313|EMBL:SCG49447.1};
GN ORFNames=GA0070213_10414 {ECO:0000313|EMBL:SCG49447.1};
OS Micromonospora humi.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=745366 {ECO:0000313|EMBL:SCG49447.1, ECO:0000313|Proteomes:UP000199360};
RN [1] {ECO:0000313|EMBL:SCG49447.1, ECO:0000313|Proteomes:UP000199360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45647 {ECO:0000313|EMBL:SCG49447.1,
RC ECO:0000313|Proteomes:UP000199360};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
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DR EMBL; FMDM01000004; SCG49447.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5HU75; -.
DR STRING; 745366.GA0070213_10414; -.
DR Proteomes; UP000199360; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR007267; GtrA_DPMS_TM.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48090:SF7; RFBJ PROTEIN; 1.
DR PANTHER; PTHR48090; UNDECAPRENYL-PHOSPHATE 4-DEOXY-4-FORMAMIDO-L-ARABINOSE TRANSFERASE-RELATED; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR Pfam; PF04138; GtrA; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022676};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..204
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
FT DOMAIN 290..403
FT /note="GtrA/DPMS transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04138"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 89853 MW; ACF8930165F301E7 CRC64;
MDRVGPGVRD RRAEPDARLK ELRTADEGRP PRLTVIVPTR NEAANIPLLL ARLGPLLAPL
DAELLVVDDS DDGTPGVLTQ VAAEAAITVR LLHRPPHARP GGLGGAVLLG AAHARGEWVL
VMDADLQHPP EAAATLARIA MRHDVDVVIG TRYAGNGSSG GLDGILRVAT SSWATRLVKG
MFPRRLATVS DPMSGLFAFR RSAVRLDRMN PLGFKVLLEL LVRHPGARVA EVAYDMAPRH
GGRSKASLRE GMTFLRHLAR LRGRRLVGQI RRSPRTRAER LRELGRMVAF GMIGLSGMVV
NTAALWFCYE PARMHHLVGA ALATQVSTSW NFLLVDSLIY RRNRHGSFAA RAARFFLLNN
VLLLLRLPVL QALVWAGVGV LVANAATLVA LFLVRFLVND RVIYTAVDKA RRDPVRLLVA
GAAEAPSTPS RRRYQYLKYR YDVAGVVTIG SQIMLPELEF FRAQWVADSD VDIAVRVSDV
GGRGPQRRAA MTQYADQSVL RYEEQLGRLG ANFRIQLGPP IEIQVGPLLA RSPHVVYTNI
VEALLRFVMV ARGHMLLHSA CVTLDGVGVM LSALTDTGKT ATVLRLLRDH GGLFLSDDMT
IVRPDGVATC FPKPLTISAH TLRAVQAQDL TPAEWRRLQL QSRLHSKGGR SLALTLSRFN
LPIMGINALT QLLIPPPKYS VDRLVPCRIG TTTRVEELFV IERGKPDIHE LDATDTLERM
IENTDDAYGF PPFRYLAPSI TIDGHGYAQL RAREREILAG FLSHVRSRVV ASDTFGWADD
IPRLLREERA DRRTPVVPAQ PWPRWSGDLT TAGGPA
//
