ID A0A1C5ICU2_9ACTN Unreviewed; 712 AA.
AC A0A1C5ICU2;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=ATP-dependent DNA helicase, RecQ-like {ECO:0000313|EMBL:SCG56222.1};
GN ORFNames=GA0070614_2610 {ECO:0000313|EMBL:SCG56222.1};
OS Micromonospora coxensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=356852 {ECO:0000313|EMBL:SCG56222.1, ECO:0000313|Proteomes:UP000198215};
RN [1] {ECO:0000313|EMBL:SCG56222.1, ECO:0000313|Proteomes:UP000198215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45161 {ECO:0000313|EMBL:SCG56222.1,
RC ECO:0000313|Proteomes:UP000198215};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT607753; SCG56222.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5ICU2; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000198215; Chromosome i.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SCG56222.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 35..212
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 242..396
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 712 AA; 76165 MW; 48ED915F27354BEC CRC64;
MSQDRAAVRE RAEAVLRRLA GEHATLREDQ WRAIEALVVD RRRVLCVQRT GWGKSAVYFV
ATALLRERPD AAGPTVIVSP LLALMRNQVE SAARAGIRAR TINSANLDEW DEITAEIHAG
AVDVLLISPE RLNNPDFRDG VLPKLAATTG LLVVDEAHCV SDWGHDFRPD YRRLRTFLAG
LPDHTPVLAT TATANARVTT DVAEQLSTGD GSDALVLRGT LDRESLRLAV LDLPSPAHRL
GWLADHLDRL PGSGIIYTLT VAAAGETAEF LRSRGWSVAS YTGQAEDADR RAAEQDLLDN
KIKALVATSA LGMGFDKPDL GFVVHLGAPP SPIAYYQQVG RAGRAVEHAE VLLLPGVEDA
AIWRYFASLA FPPEEQVRAV LAALHTDRPL STQALEPLVD LRRARLELML KVLDVDGAVR
RVRGGWLATG EPWVYDEARL RRVAQARTAE QQAMREYAAT PGCRMRYLRE CLDDAGATDC
GRCDNCAGPL FTPEVSDAAL STAQTFLGRP GVQVPPKKLW PTGLEAVGVP LKGRIPPAEQ
ALPGRAVGRL SDLGWGGRLR ALVGPDAADG PVPDDVAAAV VDVLKAWAHG DDPWPRRPVG
VVAVGSRTHP ALVGSLAERI AAVGRLPLLG QVVPTGPTGA GGPRGNSAQR VRTLHDAFAV
PADLADALAG LDGPVLLVDD LVDSGWTMAM VARLLRRTGA PDVLPLALAV AG
//
