ID A0A1C5IN18_9ACTN Unreviewed; 383 AA.
AC A0A1C5IN18;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN ORFNames=GA0074704_3623 {ECO:0000313|EMBL:SCG59727.1};
OS Micromonospora siamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=299152 {ECO:0000313|EMBL:SCG59727.1, ECO:0000313|Proteomes:UP000198210};
RN [1] {ECO:0000313|EMBL:SCG59727.1, ECO:0000313|Proteomes:UP000198210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45097 {ECO:0000313|EMBL:SCG59727.1,
RC ECO:0000313|Proteomes:UP000198210};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR EMBL; LT607751; SCG59727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5IN18; -.
DR Proteomes; UP000198210; Chromosome i.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:UniProt.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR43856; CARDIOLIPIN HYDROLASE; 1.
DR PANTHER; PTHR43856:SF1; MITOCHONDRIAL CARDIOLIPIN HYDROLASE; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198210};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..383
FT /note="phospholipase D"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008718875"
FT DOMAIN 321..351
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 383 AA; 40872 MW; DF47ED63A871594B CRC64;
MRIPTILATA ASATLLSTLA AVPAAASTVS QPCQGAPTNP VTTGAVLNNP AAGDPTAVVR
QICGLVRQAP AGSRIRIAHF VISGAAGLDF AGELIAARRR GVDVQLVLDG WQVTNPAVQA
LRAELGTDRS GGSWLHVCTG LSPEGNTAAC IGTKGNHNKF YLFSTTGGQS EVVVQSSANF
TDVNSATYWN NAMTLVGNHR LYAAYDAYFE DLAAERRTED YYRTVTTGMP GGSVTAYFFP
RAEGDPIVEQ LDKVGCGADA TIRIGMSEWD SYRIGIAERI VALAERGCQV RIVHGLMDDE
VHALLSSHPN ITLRELNSST LPGRIHSKFL LVENGGARFV MTGSPNFNRT SLRRNDEAMV
RTNIASVYEQ YRAGFEAMYA VAG
//
