ID A0A1C5J421_9ACTN Unreviewed; 613 AA.
AC A0A1C5J421;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=GA0074704_4097 {ECO:0000313|EMBL:SCG65307.1};
OS Micromonospora siamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=299152 {ECO:0000313|EMBL:SCG65307.1, ECO:0000313|Proteomes:UP000198210};
RN [1] {ECO:0000313|EMBL:SCG65307.1, ECO:0000313|Proteomes:UP000198210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45097 {ECO:0000313|EMBL:SCG65307.1,
RC ECO:0000313|Proteomes:UP000198210};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
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DR EMBL; LT607751; SCG65307.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5J421; -.
DR Proteomes; UP000198210; Chromosome i.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000198210};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..613
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008719303"
FT DOMAIN 57..372
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 411..612
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 613 AA; 64596 MW; 5C5FC376D4DF109B CRC64;
MTRHHRRRVR RPLSLALLLL AVTALVAPTS ATAAALPYQD PTLPVATRVA DLLSRMTLDE
KIGQMTQAER GSVTNADLTT YRLGSILSGG GSAPSPNTAT GWADMYDGFQ RAALATPLAI
PMIYGVDAVH GHNNVYGATI FPHNIGLGAT RDPALVQQIG QAVAEEVSGT GIDWDFAPCL
CVARNDRWGR TYESFGETPD IPSSMTTFVT GLQGATLGGP TSVLATAKHY LGDGGTTGGD
DQGDTALSEA DLRAIHLPPF QAAIQRSVGS VMISYSSWNG VKLHGNAYLI NTLLKGELGF
TGFVVSDWNG IDQIDGASGF TAAEVTAAIN AGIDMVMVPT AWKTFVSTLR AEVQNGHVAL
SRIDDANRRI LTKKFELGLF ERPYTDRSLT PTVGDAAHRA LARQAVRESQ VLLKNSGGVL
PLARDNNKIF VAGKNADNIG NQSGGWTISW QGSSGNITPG TSVLQGIRAA VGPTSTVTYN
QRGTGIDASY RAAIAVVGET PYAEGQGDRT GSMSLDRDDL RTISTLRKAG VPVIVVLASG
RPLDVAAELP NWNALLASWL PGTEGAGVAD VLFGGYAPTG KLPMTWMNSV SQQPINAGDG
QVPLFPQGYG LTW
//
