ID A0A1C5JQJ8_9ACTN Unreviewed; 359 AA.
AC A0A1C5JQJ8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=MerR HTH family regulatory protein {ECO:0000313|EMBL:SCG72854.1};
GN ORFNames=GA0074704_4820 {ECO:0000313|EMBL:SCG72854.1};
OS Micromonospora siamensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=299152 {ECO:0000313|EMBL:SCG72854.1, ECO:0000313|Proteomes:UP000198210};
RN [1] {ECO:0000313|EMBL:SCG72854.1, ECO:0000313|Proteomes:UP000198210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45097 {ECO:0000313|EMBL:SCG72854.1,
RC ECO:0000313|Proteomes:UP000198210};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the beta sliding clamp family.
CC {ECO:0000256|ARBA:ARBA00010752}.
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DR EMBL; LT607751; SCG72854.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5JQJ8; -.
DR Proteomes; UP000198210; Chromosome i.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00140; beta_clamp; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.10.150.10; DNA Polymerase III, subunit A, domain 2; 2.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR046938; DNA_clamp_sf.
DR InterPro; IPR001001; DNA_polIII_beta.
DR InterPro; IPR022637; DNA_polIII_beta_cen.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR PANTHER; PTHR30478:SF0; BETA SLIDING CLAMP; 1.
DR PANTHER; PTHR30478; DNA POLYMERASE III SUBUNIT BETA; 1.
DR Pfam; PF02767; DNA_pol3_beta_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SMART; SM00480; POL3Bc; 1.
DR SUPFAM; SSF55979; DNA clamp; 2.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000198210};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 7..75
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 359 AA; 38203 MW; F019DE2F0B769D7E CRC64;
MESELRSIGE LARASGLTVS ALRFYDRSGV LAPALVDPVT GYRWYAEDQV APARLVAGLR
RVGMPLAGIV EALRHRHEPA VVGALLDAHL RRLEDGLADA RRELFRIRTL IDPEESEMTT
RLALSRTDLA AAVDAVRFAV GADPELPVLA GVLLDVEPDG VRLIATDRHR LATARVGAEV
SGPPVRFLLP VAAVDELRAL LDAVGPAVEL TVTPDELTAA VADRVVRAAP LPYDFPDLHR
LLRDAVSATP ALRVPLDVAA LRAALTAPDV PVQVREHEGA RYEVTVLGLA GGGLRVLAAD
EPATAEVVRV GVNRHYLLDA LDAGGAGQLV LELDGPITPL AVRRPGDGDA FSILMPVRL
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