ID A0A1C5JR92_9ACTN Unreviewed; 1013 AA.
AC A0A1C5JR92;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Tetratricopeptide repeat-containing protein {ECO:0000313|EMBL:SCG73027.1};
GN ORFNames=GA0070609_4793 {ECO:0000313|EMBL:SCG73027.1};
OS Micromonospora echinaurantiaca.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47857 {ECO:0000313|EMBL:SCG73027.1, ECO:0000313|Proteomes:UP000198217};
RN [1] {ECO:0000313|EMBL:SCG73027.1, ECO:0000313|Proteomes:UP000198217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43904 {ECO:0000313|EMBL:SCG73027.1,
RC ECO:0000313|Proteomes:UP000198217};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; LT607750; SCG73027.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C5JR92; -.
DR Proteomes; UP000198217; Chromosome i.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF13424; TPR_12; 2.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 6.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000198217}.
FT DOMAIN 1..95
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..95
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 73..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1013 AA; 108213 MW; A34D2A43BF25996C CRC64;
MLRISVLGPV QVTHGDRPVR LGPKLVELLA ILLVEAGSAV PASRVVQLLW DATPPAGARA
TLRSHVSHLR RALETNPAEH HRVKAERDPR PALKAESGEH HPPEAAPSVR EAALREPSAP
EAPTLGERPA REAERGPRLT EAEWRARRAS RTASGVAPVS DPTAATPIIR TVGSGAGSAY
CLDLPPDTVD ADRFERWCAD GRRLVAAGET ALTERGVALL RDALALWRGS AFADLADRPF
VRPRAGQLAA GRRAARRGYA EGLAALGRHA EAVAQLSAAL ADDPYDEAVR RLLALSLYAE
QRVDEAAEVC REGVVLLGER GLDAPELQEL QRDILRRLVP SPRGAADPVK LARPCLLPPD
PPQFVGRAED LAAARRLLLS PADGSPTVLV SGLAGVGKTL FAVRLAHTLR ADFPDGQLYV
DMRGFDPDGT PLGAGAAVRG FLDALAVPPD RVPATLEAQA GLYRSLLAGR RVLVVVDNVR
DADQVRPLLP GAAGCATVVV SRNQLPALVV AEGARPLRLD LLTDGESREL IGRRLGAARL
AGEPGAVRQI VHACGRLPLA LAIVAARAAS HPEFTLDALA GELRGDGGGL DAFAVGGTDV
RAVFSWSYHG LTAPAAGLFR LLAAHPGPEV TVAAAASLAA APPEEVRAAV RELAAAHLLV
EHVPGRYALH DLLRAYANEL ADDGGRRAAL RRTLDHYLHT ALAADRLLWP HRDPLASPAA
APGVRPEVFA DRDAALAWFT AEHPVLLAAL DRAERAGLDG HVWRLAWAAA NFLARRGHWR
DWVRVGQAAV AAARRQDDRA AEAEAHRILS GAYVRLRDFD AAREHYGRAL ELFGGLGDLV
GQGFTRRSLG WLCEQQGDVR AALGHDLAAL ELFERAGHER GVANTHNSVG WCHALLGDHE
PAISHCRRSL ALLERLGDPV GMAGAWDSLG YAYRQVDPHE ALACYRQALG LYRQLGDRMN
EAVTLRQLGE TQHAGGDSAA ARESWRQALD ILTDLDHPDA ERVRTLLAGA TTA
//
