ID A0A1C6LIV2_9BURK Unreviewed; 454 AA.
AC A0A1C6LIV2;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Uracil-xanthine permease {ECO:0000313|EMBL:SCK06479.1};
GN ORFNames=VAR608DRAFT_0062 {ECO:0000313|EMBL:SCK06479.1};
OS Variovorax sp. HW608.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1034889 {ECO:0000313|EMBL:SCK06479.1, ECO:0000313|Proteomes:UP000198203};
RN [1] {ECO:0000313|Proteomes:UP000198203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HW608 {ECO:0000313|Proteomes:UP000198203};
RA Varghese N., Submissions Spin;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; LT607803; SCK06479.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C6LIV2; -.
DR OrthoDB; 9779092at2; -.
DR Proteomes; UP000198203; Chromosome i.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 59..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 454 AA; 47251 MW; CA2E38059C32B74D CRC64;
MSESYLPRWQ KVSATAGAVV TPDQRLPWPQ TAAMGVQHVI AMFGATVLAP ILMGFNPNVA
ILMSGIGTLL FFFITGGRVP SYLGSSFAFI GVVIAATGYA GSGPNTNLGV ALGGIVVCGL
VYVLIGVLVA LTNERRTKRA PVKGLEGMEV EEVESDVAVH WIERLMPPVV TGAVVAVIGL
NLASVPIKNM APTGFDTWMQ LVTFLSVGLI AVYTRGMIQR LLILMGLIAA SIIYALLTNG
LGMGKPIDLT PLAAAPWFGM PTFSSPVFDV NAMLLIAPVA VILVAENLGH IKAVSAMTGR
DLNPYLGRAF IGDGVATMVS GAFGGTGVTT YAENIGVMAA TKIYSTAIFV VAALIALVLG
FSPKFGALVQ AIPLSVMGGV SIVVFGLIAV AGAKIWVDNR VDFSRNKNLI TAAITLILGT
GDFTLRFGQF ALGGIGTATF GAILLYALLN RSDA
//
