ID A0A1C6LKD5_9ACTN Unreviewed; 523 AA.
AC A0A1C6LKD5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=NADH:ubiquinone oxidoreductase, NADH-binding subunit (Chain F) {ECO:0000313|EMBL:SCK06966.1};
GN ORFNames=H181DRAFT_00229 {ECO:0000313|EMBL:SCK06966.1};
OS Streptomyces sp. WMMB 714.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1286822 {ECO:0000313|EMBL:SCK06966.1, ECO:0000313|Proteomes:UP000182206};
RN [1] {ECO:0000313|Proteomes:UP000182206}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WMMB 714 {ECO:0000313|Proteomes:UP000182206};
RA Varghese N., Submissions Spin;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; FMHJ01000001; SCK06966.1; -; Genomic_DNA.
DR RefSeq; WP_045862228.1; NZ_FMHJ01000001.1.
DR AlphaFoldDB; A0A1C6LKD5; -.
DR STRING; 1286822.GCA_000964305_00228; -.
DR OrthoDB; 3396880at2; -.
DR Proteomes; UP000182206; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR PANTHER; PTHR11780:SF10; NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11780; NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13459; Fer4_15; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000182206};
KW Ubiquinone {ECO:0000313|EMBL:SCK06966.1}.
FT DOMAIN 332..373
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 523 AA; 54812 MW; FDBBF8E20A01D434 CRC64;
MTSVVPSPVS ASNADAVPSL ASFGPPRLLA GLGTGGAWHR RLDRVGHLTV HGQMPELRLQ
EVVDLAENID LRGRGGAGFP FARKLQSVIE SARRRQDART VVVVNGSEGE PSCLKDTALL
LYTPHLVIDG ALLVARALKA EEVSICVARP DVERSVRDAV AERGPGAPRV RVARMPEAFV
TGESSSLVNG LNQLPVVPSG TGVRASESGV AGLPTMLSNT ETYAQLAIAA RLGALDFRNV
GLPTEPGTVL LTVAGERVVE TPFGAPLPYI LGLCGMDPGQ GVLIGGYHGK WLQRDLAWSA
RISRESLDSY GSTLGAGAVL PLPEGTCPAG ELELVARWMA KESAGQCGPC VLGLPALADT
IAWAADGGGR EALDALWARA KAVKGRGACS HPDGTSRLVE STLDAFPEEF ELHALGQGCG
RPVLSSLSVP GEGQVSQARG IRGIRSDRGR TAPGVPQKSR RLVVDWTLCQ GHGLCAGVVP
DMVELDVDGY PTGASAAIPD YMHKQAQRAV RRCPALALRI VEK
//
