ID A0A1C6LUL0_9ACTN Unreviewed; 231 AA.
AC A0A1C6LUL0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases {ECO:0000313|EMBL:SCK10196.1};
GN ORFNames=H180DRAFT_00540 {ECO:0000313|EMBL:SCK10196.1};
OS Streptomyces sp. WMMB 322.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1286821 {ECO:0000313|EMBL:SCK10196.1, ECO:0000313|Proteomes:UP000182082};
RN [1] {ECO:0000313|EMBL:SCK10196.1, ECO:0000313|Proteomes:UP000182082}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WMMB 322 {ECO:0000313|EMBL:SCK10196.1,
RC ECO:0000313|Proteomes:UP000182082};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMHI01000001; SCK10196.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C6LUL0; -.
DR STRING; 1286821.GCA_001418285_00539; -.
DR OrthoDB; 3678076at2; -.
DR Proteomes; UP000182082; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd00092; HTH_CRP; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF74; REGULATORY PROTEIN CYSR HOMOLOG; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR PRINTS; PR00034; HTHCRP.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SCK10196.1};
KW Transferase {ECO:0000313|EMBL:SCK10196.1}.
FT DOMAIN 21..120
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 155..223
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 231 AA; 24657 MW; 5DF5CF9552BC9E67 CRC64;
MPGSVSADTE AQWRSLSGIP LLAGLPDDQL RTLWTDSLAR DWPAGDALRN AGDPASHLVL
LLRGRVAATA ATRSGRVVRF GEWSGPCALD KVAVIDGHGH TATFTALTPC SIRTLPRDRF
LAAIDDVPSV RGHVLRVLAG QARSQQEKLT ATATMPAEAR LAAWLLNEAA SDAGGSVRLP
GTQQVLADLL GVTRVTVNRA LSRLRRDGLI EFDRRTVTVL APELLALRTH G
//
