ID   A0A1C6MAD2_9ACTN        Unreviewed;       925 AA.
AC   A0A1C6MAD2;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Acyl-CoA synthetase (NDP forming) {ECO:0000313|EMBL:SCK15759.1};
GN   ORFNames=H180DRAFT_01049 {ECO:0000313|EMBL:SCK15759.1};
OS   Streptomyces sp. WMMB 322.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1286821 {ECO:0000313|EMBL:SCK15759.1, ECO:0000313|Proteomes:UP000182082};
RN   [1] {ECO:0000313|EMBL:SCK15759.1, ECO:0000313|Proteomes:UP000182082}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WMMB 322 {ECO:0000313|EMBL:SCK15759.1,
RC   ECO:0000313|Proteomes:UP000182082};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FMHI01000002; SCK15759.1; -; Genomic_DNA.
DR   RefSeq; WP_055484773.1; NZ_FMHI01000002.1.
DR   AlphaFoldDB; A0A1C6MAD2; -.
DR   STRING; 1286821.GCA_001418285_01047; -.
DR   OrthoDB; 190266at2; -.
DR   Proteomes; UP000182082; Unassembled WGS sequence.
DR   GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:InterPro.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR043938; Ligase_CoA_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   Pfam; PF13549; ATP-grasp_5; 1.
DR   Pfam; PF13380; CoA_binding_2; 1.
DR   Pfam; PF19045; Ligase_CoA_2; 1.
DR   Pfam; PF13607; Succ_CoA_lig; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
FT   DOMAIN          21..173
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
FT   REGION          833..855
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          904..925
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   925 AA;  96620 MW;  31F9E91AD046D0D0 CRC64;
     MTYAAPRMAE TYALLTDGRT VQIRPARPSD RGQVEALYEG MSQQDHKQRF FGAGAGLRER
     EIDRVFGPGR SDLLVLLALH GSQLIGTAEY EKLLEEPAAA EIALAVADGF QHCGVGTLLL
     EHLAHAARAE HITTFTADAL AENRDVLDVF ENLGLRYERT FENGEVRCRV DLTPHESYLA
     AVDARGSTAD VASMRPLLQP RSVAVVGAGR SPKSVGRAVL RNLRRSGFTG AVHGINPHAA
     SIEGFACRPA VSELPHTPDL AVIAVPAHAV PEAADQCGRF GVRALTVLTS GLDEALGGAL
     LDICRHYGMR LVGPDCLGIA NTEDGIRLDA TFAADLPEPG TAGVAVQSGG VGIALLSDLA
     RLGIGVSSFV SLGDKYDVSG NDLLQWWEAD ERTRVGLLHL ESFGNPRAFS RTARRVTRLM
     PVLTVDAGRS DAGRRAAAGH TAAAATPAMT RQALFHQAGV TATLSLGDLT ATAALMHSQP
     LPTGTSVAVV SNAGGTGVLT ADACDEAGLT LPELPEDVAA ELRTLLPEAA RVANPLDTTA
     AVGRGALAEC VELLSTRAPV DAVLVVLVPT ATAAAGGDDL VRAAASAEAP GGGRTLVTVL
     PDQSERVRLV RTPGGTGPAA VPAYADPQDA ARALAHAAAR SRWLAHPPGH VPDLSGRVDT
     DRARTLVQAA LSEHPEGTWL DPDRCGHLLD LYGIPRVPQS VVRDRAGAVR EAARLAPGGG
     RLALKAYGPD LLHKSAHGAV VLDLEGPDAA GGAFRDLRNR LGERMDGAIV QPMAGRGVEL
     IAGVVQDDVF GPLVLFGLGG TATDVLADHA ARLAPLTDRD VHELVAAPLC APTLRGQGQG
     QGQGQGRGRG RGSGEAVDLP ALEDLLLRVS KMADDLPELA EADLNPVLAR PDGVAVLDCR
     IRLAHPRPPR PGRGTGPHAY PRRLR
//