ID   A0A1C6MEV2_9NEIS        Unreviewed;       853 AA.
AC   A0A1C6MEV2;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=PSELUDRAFT_1812 {ECO:0000313|EMBL:SCK17261.1};
OS   Vogesella sp. LIG4.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC   Chromobacteriaceae; Vogesella.
OX   NCBI_TaxID=1192162 {ECO:0000313|EMBL:SCK17261.1, ECO:0000313|Proteomes:UP000198213};
RN   [1] {ECO:0000313|EMBL:SCK17261.1, ECO:0000313|Proteomes:UP000198213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LIG4 {ECO:0000313|Proteomes:UP000198213};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; LT607802; SCK17261.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C6MEV2; -.
DR   OrthoDB; 8579121at2; -.
DR   Proteomes; UP000198213; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.450.350; CHASE domain; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR006189; CHASE_dom.
DR   InterPro; IPR042240; CHASE_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR   PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR   Pfam; PF03924; CHASE; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF13188; PAS_8; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM01079; CHASE; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198213};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          348..405
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          625..846
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   853 AA;  94446 MW;  42938DEDFB28CB8D CRC64;
     MKTEFKPATL LISSLVLAGS LWLLAMLLLQ QAEQNASRSR QLGQATQRIT LLTQQLQQLL
     QNGQTATELL LSGDNDASGS GSFTRYAPYV LSANPAFDFL TVVQRVDQRQ REAVELNQGL
     LLRQFEGNRL MPASVRPAYF PVAQQYPDDS EALPLHLDLG AQSDVGHALQ HAIADGLPAL
     VQLRTGSSQR LALFFSPKTR PLPLLLGIGL NPAQLLTTSS QGAASEQLRL RILIQDRQHP
     LLADSHPNLP PESLPLLRAS RIIGGQQLTF EVMPVGDDDS TGHGLLLAGV LLLAAIVLMG
     SAGSRLSRQN RQKLQYQSGM INRLQDSNVT LKTQQERQRE RIKPLQDTEE RHRALLAQQS
     DGLILLNDHG QVILVNPAAA RLIGQQQDAL LQLPAGALIS ELHHPPHSSF AEHVAPLIGH
     PFEALLICDQ SFMLQVEMSI SLIMPDHTAP FYLVMCRNIA ARKEREAALL RLTDTLAEQV
     ETRSRQLSAL LDASPMAMAY IVDRHFKQVN KAFLTLFQRR EDEIIEHSTR ILYDSDEQFL
     RTGRIAYPAL NNGEISQDDM LLARGGGDNI WVRMFGRAVK PGQPALGSVW LYQDISAQRT
     TEEALRRARD LAEETSRAKT EFLANMSHEL RTPLHAILGF AEMGQQQEDP AALSRLHRYF
     ERIHHSGSRL LSLLNELLDL SKMEVGRMEY AMQRSDLQHV IRECLDELRG QAEQQGISLL
     FVPLPNEVLV DMDAFRIGQV VRNLLSNAIK FSPQGARVSV DIVPGSSPEA PLRVDVRDYG
     PGVPEHEREQ IFDKFIQSSL TKTGAGGTGL GLAICREIVH AHGGAIAVHN AEGGGAIFSF
     TLPRRQYGLN KEK
//