ID   A0A1C6MUJ8_9NEIS        Unreviewed;       504 AA.
AC   A0A1C6MUJ8;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE            EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN   ORFNames=PSELUDRAFT_2602 {ECO:0000313|EMBL:SCK22539.1};
OS   Vogesella sp. LIG4.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC   Chromobacteriaceae; Vogesella.
OX   NCBI_TaxID=1192162 {ECO:0000313|EMBL:SCK22539.1, ECO:0000313|Proteomes:UP000198213};
RN   [1] {ECO:0000313|EMBL:SCK22539.1, ECO:0000313|Proteomes:UP000198213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LIG4 {ECO:0000313|Proteomes:UP000198213};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT607802; SCK22539.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C6MUJ8; -.
DR   OrthoDB; 9813903at2; -.
DR   Proteomes; UP000198213; Chromosome i.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd12914; PDC1_DGC_like; 1.
DR   CDD; cd12915; PDC2_DGC_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198213};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        301..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          367..503
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   504 AA;  55427 MW;  9A41C84783C43370 CRC64;
     MAGDDPEKSP ASGKLLQRHP ALILAFAVLL VGVMLGLVGN VLLRQRQEMV LHAADNAENL
     ALISEREITR TLQLFDLSIQ AVVDGVVNKE VLALSPGMRQ MVLFDRSATA GKYLGSLLFV
     DDHGNIVFDS AAETPRHGNF VDRPWFTAHL HNADAGLYIS PPYRSRLRNG MQSIALSRRV
     QHADGSLAGV VVGAIDLEYF RALFSGLNLG GDGTINLMSG SGTVIMRLPY RDDWIGANLA
     NSTNFLRARQ QHERFFVGTS ALDGRTRLYV VRTFKTLPLV ISVAQGLDEV YAQWWRQARM
     VVLLISLLAV SLLAAAWLLT REFQSRLKAE RELLLLAEVD GLTALNNRRK FDALFEREWL
     RAKRLHHPVA ALFVDIDWFK GFNDSYGHQR GDDVLRQVAH VIAGAPKRPA DVSARFGGEE
     FVLVLPDTNA RGAAKVAQRI VDEVRALQIP HAGSSYGCVT VSVGYACSDM GVIEDGKALI
     AQADRALYLA KSRGRNRAVS ALES
//