ID A0A1C6NU87_9ACTN Unreviewed; 356 AA.
AC A0A1C6NU87;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Fatty acid desaturase {ECO:0000313|EMBL:SCK34427.1};
GN ORFNames=H181DRAFT_02847 {ECO:0000313|EMBL:SCK34427.1};
OS Streptomyces sp. WMMB 714.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1286822 {ECO:0000313|EMBL:SCK34427.1, ECO:0000313|Proteomes:UP000182206};
RN [1] {ECO:0000313|Proteomes:UP000182206}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WMMB 714 {ECO:0000313|Proteomes:UP000182206};
RA Varghese N., Submissions Spin;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
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DR EMBL; FMHJ01000006; SCK34427.1; -; Genomic_DNA.
DR RefSeq; WP_045864714.1; NZ_FMHJ01000006.1.
DR AlphaFoldDB; A0A1C6NU87; -.
DR STRING; 1286822.GCA_000964305_02836; -.
DR OrthoDB; 104711at2; -.
DR Proteomes; UP000182206; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR CDD; cd03506; Delta6-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR19353:SF19; DELTA(5) FATTY ACID DESATURASE C-RELATED; 1.
DR PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR Pfam; PF00487; FA_desaturase; 1.
DR PIRSF; PIRSF015921; FA_sphinglp_des; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000182206};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..326
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 39204 MW; CE1C04CB9A2D09B1 CRC64;
MTTAFAEPPA SSAPETEPQR GSDFARLSRR VADAGLLRRR PGYYTVRLTL VGLALAGGWT
AFFALGESWW QLAVAAFLGL VFGQLALAAH DLAHRQVFSG RRASEVGGRI VGNLGVGMSY
GWWMNKHTRH HANPNHEELD PDVAPDILVW SRDQARAAKG LPGFIGRHQA ALFFPLLTLE
GFNLHVSSVR ALRQPHMKRR LLEGALLFAH LAGYLAAIFA VLPAGMAVAF LFLHQAVFGV
YLGSIFAPNH KGMPTLTGDD RPDFLRRQVL TSRNVTGGRL TDIALGGLNH QIEHHLFPSM
PSPHLRRARV IVREYCAELG IAYHETGLVA SWREALRHLH EVGAPLREER RSPASS
//
