ID   A0A1C6PM51_9ACTN        Unreviewed;      1011 AA.
AC   A0A1C6PM51;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=FAD/FMN-containing dehydrogenase {ECO:0000313|EMBL:SCK44257.1};
GN   ORFNames=H180DRAFT_03896 {ECO:0000313|EMBL:SCK44257.1};
OS   Streptomyces sp. WMMB 322.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1286821 {ECO:0000313|EMBL:SCK44257.1, ECO:0000313|Proteomes:UP000182082};
RN   [1] {ECO:0000313|EMBL:SCK44257.1, ECO:0000313|Proteomes:UP000182082}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WMMB 322 {ECO:0000313|EMBL:SCK44257.1,
RC   ECO:0000313|Proteomes:UP000182082};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; FMHI01000012; SCK44257.1; -; Genomic_DNA.
DR   RefSeq; WP_055487362.1; NZ_FMHI01000012.1.
DR   AlphaFoldDB; A0A1C6PM51; -.
DR   STRING; 1286821.GCA_001418285_03879; -.
DR   OrthoDB; 9770306at2; -.
DR   Proteomes; UP000182082; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02754; CCG; 2.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          50..279
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   REGION          988..1011
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1011 AA;  108255 MW;  3EDC3B378C1C01CB CRC64;
     MTAISGDAPS PAGTAETARH VEARLRGEIE GDVLFDEYTR HLFSRDASMY AIEPLGVVFP
     RHAGDVQAAV TAAAEAGIPV VPRGAGTSLA GQTVGPGLVL DLSRHMNRIV EIDPEGRTAL
     VEAGVVQDQL NRAAAAHGLM FGPDTSTSNR ATIGGMIGNN SAGSGSIRYG MTIDHVRELD
     VVLSDSATAR LGPVDEAERG RRAGLPTLEG RLYRELPRIV EESAEATAEG MPQFWRRACG
     YRLDRLAATG AEFDLAKFVV GSEGTLVLAT RALVDLVPKP SRTVIAVGHF TSVAGAIAAT
     DDALACDPSA VEMMDRTILD LSRKKIEYAS LGSILEGDPE ALLFVSFTGD DEHELAGRLQ
     QLTALWQRHG HGYHTLQAVT PAQQGSLLKV RKSSLGLLMA ASEGTRRPLA FIEDTAVDPV
     HLGDYTRRFK QVLDRHGLNA GFYGHCSVGC LHIRPFVDTA DPVQVATMRS VAEEIKDLVR
     EYGGVNSSEH GDGLARSEFN REIFGDDLYE AMRRVKGLFD PDNRLNPGKI VDAPSMTDNL
     RDPALPPAGP LRTRLDFEVV GGMRGAADRC MNIGLCRKAG AGTMCPSYMA TLKEEDSTRG
     RANALVKALS EPDPHRALGD GRLHEVLDLC LMCKACKSEC PLGVDMATLK AESLSHHHDE
     HGIPRRSRVF ASIRRLNRIG SATAPLSNLP GRVPFLRALM DRYLGITPAR PLPAFVRGNL
     VRWFRRRGRA AASPATATGP AAPGSQGTVT YLADSFTTYT EPGIGRAAVE LLELAGWHVT
     LESRGCCGRS AFSKGLLDEA KDQARKLTKL LAQNSPAGSP VVGCEPSCLM TLRDEHRAML
     PQDPAVADVS ARVRQAEELL AEAVDDGRLR LSPDAWPAGR RILYHGHCHQ KAEVGTAATV
     ALLKRIPGAE VVELDAGCCG MAGSFGFESE HYETSMTVGS DRLFPAVRAE DDTTVIAASG
     VSCRQQIFHG TERNAWHPVE LVRAALLTGS PDTGGTGDET PATATEGEAP R
//