ID   A0A1C6QNJ0_9ACTN        Unreviewed;       131 AA.
AC   A0A1C6QNJ0;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Multicomponent Na+:H+ antiporter subunit F {ECO:0000313|EMBL:SCK56975.1};
GN   ORFNames=H180DRAFT_05330 {ECO:0000313|EMBL:SCK56975.1};
OS   Streptomyces sp. WMMB 322.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1286821 {ECO:0000313|EMBL:SCK56975.1, ECO:0000313|Proteomes:UP000182082};
RN   [1] {ECO:0000313|EMBL:SCK56975.1, ECO:0000313|Proteomes:UP000182082}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WMMB 322 {ECO:0000313|EMBL:SCK56975.1,
RC   ECO:0000313|Proteomes:UP000182082};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F
CC       family. {ECO:0000256|ARBA:ARBA00009212}.
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DR   EMBL; FMHI01000022; SCK56975.1; -; Genomic_DNA.
DR   RefSeq; WP_074467014.1; NZ_FMHI01000022.1.
DR   AlphaFoldDB; A0A1C6QNJ0; -.
DR   STRING; 1286821.GCA_001418285_05305; -.
DR   OrthoDB; 3733837at2; -.
DR   Proteomes; UP000182082; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015075; F:monoatomic ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR007208; MrpF/PhaF-like.
DR   PANTHER; PTHR34702:SF1; ANTIPORTER SUBUNIT MNHF2-RELATED; 1.
DR   PANTHER; PTHR34702; NA(+)/H(+) ANTIPORTER SUBUNIT F1; 1.
DR   Pfam; PF04066; MrpF_PhaF; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          88..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   131 AA;  13013 MW;  971BCE255C9841B2 CRC64;
     MEAVLSIVIA LLLTSGVLVT VRLVRGPSTL DRAVALDALV AVVMAGIGVL TAARQIPYYL
     PALLVLAFLG FTGSVSIARF LALRDEAGSE DPDVDDGGDR QTAGHDSAAQ PGGPGGGPEA
     SGGTAEQGSG G
//