ID   A0A1C6QP75_9BURK        Unreviewed;       774 AA.
AC   A0A1C6QP75;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Oxidoreductase alpha (Molybdopterin) subunit {ECO:0000313|EMBL:SCK57310.1};
GN   ORFNames=VAR608DRAFT_6037 {ECO:0000313|EMBL:SCK57310.1};
OS   Variovorax sp. HW608.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1034889 {ECO:0000313|EMBL:SCK57310.1, ECO:0000313|Proteomes:UP000198203};
RN   [1] {ECO:0000313|Proteomes:UP000198203}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HW608 {ECO:0000313|Proteomes:UP000198203};
RA   Varghese N., Submissions Spin;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; LT607803; SCK57310.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C6QP75; -.
DR   OrthoDB; 5287431at2; -.
DR   Proteomes; UP000198203; Chromosome i.
DR   GO; GO:1990204; C:oxidoreductase complex; IEA:UniProt.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0045333; P:cellular respiration; IEA:UniProt.
DR   CDD; cd02787; MopB_CT_ydeP; 1.
DR   CDD; cd02767; MopB_ydeP; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR037951; MopB_CT_YdeP.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR   InterPro; IPR041953; YdeP_MopB.
DR   NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR   PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   PIRSF; PIRSF000144; CbbBc; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          109..486
FT                   /note="Molybdopterin oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00384"
FT   DOMAIN          645..752
FT                   /note="Molybdopterin dinucleotide-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01568"
SQ   SEQUENCE   774 AA;  85440 MW;  576C1482689B34AD CRC64;
     MQEQRIAFYK GPAGGWGALR SVTHTLLKQD IPIKGAQTML SANQPGGFDC PGCAWPDRNH
     SSSFEFCENG VKAVAAEATA RRAGPELFDR HTVAELAQQS DFWLEDQGRL THPMVYDAPS
     DKYRPIEWDD AFALIARHLE ALPDPNQAIF YTSGRASNEA AFLYQLFVRE YGTNNFPDCS
     NMCHEPSGSG MRAQIGVGKG TVTLDDFERA DAIFIFGQNP GTNHPRMLGE LRAAHRRGAK
     IVSFNPLRER GLERFADPQD KLEMATLGST PISTHYFQLR VGGDFALVKG MMKHLVERED
     AGDAVLDHAF IAAHTTGFDA LAADLRAESW PLLERESGLT EAQIRAAAEV YRHAKSAIVC
     WGMGITQHVH AVATIQMLVN LLLMRGNIGR EGAGPCPVRG HSNVQGDRTM GIWEKPPAAL
     LDRLRDVFGF EPPRSNGWDT VESIRAMLDG KGKVFFALGG NFAAATPDTP TTWKALQKCD
     LTVHVTTKLN RSHVVHGREA LILPCLGRTE IDMQAGGPQG VTVEDSMGMV HISGGINPPA
     SVHLLSEPAI VARLAAATIG QRSRTPWLWL IEDYGRIRDR IEAVFDDFKD FNRRVAVPGG
     FRLRNAASER VWETPTRRAN FATHAVPLDT PSHLARARVR DAIVFTLLTT RSHDQYNTTI
     YGLDDRYRGV FGQRRVVFIH QDDIRALGFK DGDWVDLHTV WDDGEERRAD RFRLVAYDIP
     RGNLAAYYPE TNPLVPLDAV ARNAGTPASK SIPVILTLHD ATPEAEAAAE EVAP
//