ID A0A1C6RFL0_9ACTN Unreviewed; 332 AA.
AC A0A1C6RFL0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=GA0070616_0881 {ECO:0000313|EMBL:SCL15948.1};
OS Micromonospora nigra.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=145857 {ECO:0000313|EMBL:SCL15948.1, ECO:0000313|Proteomes:UP000199699};
RN [1] {ECO:0000313|EMBL:SCL15948.1, ECO:0000313|Proteomes:UP000199699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43818 {ECO:0000313|EMBL:SCL15948.1,
RC ECO:0000313|Proteomes:UP000199699};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMHT01000003; SCL15948.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C6RFL0; -.
DR STRING; 145857.GA0070616_0881; -.
DR OrthoDB; 9805663at2; -.
DR Proteomes; UP000199699; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000199699}.
FT DOMAIN 18..330
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 332 AA; 35206 MW; E157B31760A33F5F CRC64;
MSSNREIHLA SRPQGWPTED NFRLVETEVP SPGPGQIVVR NQYISVDPYM RGRMNDVKSY
VPPFALDAPL DGGAVGEVVA GEAEGVRPGD TVLHGLGWRE YALLDARAAR VVDPSLAPVA
AYLGVLGMTG LTAYAGLLDV AAMKPGETVF VSGAAGAVGS MVGQIARLRG AGRVVGSAGS
AAKVQRLRAL GFDAAFDYHD GPVRDLLKEA APDGVDVYFD NVGGEHLEAA ISSLRLHGRA
AICGMIAQYN DTEPAAAPHN LAMLIGKRLT LRGFLVSDFG HLREQFEQEV SGWLRDGTLS
YDETVVDGIE NAPSAFLGLL RGENLGKMLV RV
//
