ID   A0A1C6RR45_9ACTN        Unreviewed;       363 AA.
AC   A0A1C6RR45;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Mannose-6-phosphate isomerase, type 2 {ECO:0000313|EMBL:SCL19541.1};
GN   ORFNames=GA0070624_1781 {ECO:0000313|EMBL:SCL19541.1};
OS   Micromonospora rhizosphaerae.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=568872 {ECO:0000313|EMBL:SCL19541.1, ECO:0000313|Proteomes:UP000199413};
RN   [1] {ECO:0000313|Proteomes:UP000199413}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45431 {ECO:0000313|Proteomes:UP000199413};
RA   Varghese N., Submissions Spin;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMHV01000002; SCL19541.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C6RR45; -.
DR   STRING; 568872.GA0070624_1781; -.
DR   OrthoDB; 9806359at2; -.
DR   Proteomes; UP000199413; Unassembled WGS sequence.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0005976; P:polysaccharide metabolic process; IEA:InterPro.
DR   CDD; cd02509; GDP-M1P_Guanylyltransferase; 1.
DR   InterPro; IPR049577; GMPP_N.
DR   InterPro; IPR001538; Man6P_isomerase-2_C.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR   Pfam; PF01050; MannoseP_isomer; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:SCL19541.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199413};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          4..282
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
FT   DOMAIN          322..360
FT                   /note="Mannose-6-phosphate isomerase type II C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01050"
SQ   SEQUENCE   363 AA;  38599 MW;  39F35BE74717690A CRC64;
     MFYAVIPAGG SGTRLWPLSR AGHPKFLHPL TGTRASLLQA TVDRLEPLTT PERTLVVTGA
     AHVAAVARQL AGLPEENILV EPSQRDSCAA IALAAAVIAL RDPEAVMGSF AADHLIGDPA
     RWADTVREAI RGAEQGLLMT VGITPTRPET GYGYLETGEP VGEGPLRPVI EFKEKPAAEV
     AEAYFRSGRH LWNASMFVWR VDVFLAELAR QQPALHAGIT AIAAAWGTPE QDDILGTVWP
     TLPKISVDYA VMEGAATAGR VATVPGDFGW NDVGDFHTLG EVLPADACGN VVLGVDGKPG
     VLLRDSKSLV VVPQSGRLVA VLGVHDLIVV DTPDAVLVCP RDRAQDVKKL VDELKERGEE
     GYV
//