ID A0A1C6U0S0_9ACTN Unreviewed; 1931 AA.
AC A0A1C6U0S0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=WD40 repeat {ECO:0000313|EMBL:SCL47493.1};
GN ORFNames=GA0070603_0393 {ECO:0000313|EMBL:SCL47493.1};
OS Micromonospora chersina.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47854 {ECO:0000313|EMBL:SCL47493.1, ECO:0000313|Proteomes:UP000198605};
RN [1] {ECO:0000313|EMBL:SCL47493.1, ECO:0000313|Proteomes:UP000198605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44151 {ECO:0000313|EMBL:SCL47493.1,
RC ECO:0000313|Proteomes:UP000198605};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMIB01000002; SCL47493.1; -; Genomic_DNA.
DR STRING; 47854.GA0070603_0393; -.
DR OrthoDB; 134501at2; -.
DR Proteomes; UP000198605; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00200; WD40; 2.
DR Gene3D; 2.160.20.80; E3 ubiquitin-protein ligase SopA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 5.
DR InterPro; IPR001646; 5peptide_repeat.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF637; WD REPEAT DOMAIN 5; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF00805; Pentapeptide; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF00400; WD40; 11.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00255; TIR; 1.
DR SMART; SM00320; WD40; 15.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF141571; Pentapeptide repeat-like; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50837; NACHT; 1.
DR PROSITE; PS50104; TIR; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 11.
DR PROSITE; PS50294; WD_REPEATS_REGION; 10.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 12..145
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT DOMAIN 714..832
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 1284..1325
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1369..1410
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1452..1493
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1494..1535
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1536..1577
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1578..1619
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1662..1703
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1704..1745
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1746..1787
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1788..1820
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1830..1871
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 151..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1931 AA; 210312 MW; 2B726173A654B883 CRC64;
MAVGAHPTRS DRPIDFFISY SPADERWATW LAWEFEAAGY RTLLQAWDFV AGTNFIDFMD
RGVREAEVVV AVLSERYLHS TYGKLEWQAA LRADPDGTGN KLVTVRVEDC PIDGLLATIT
YVDLVGVSDP AQARGRVLDR IRQTLDGRAK PMRQPAFPHH PADPPGVLAA PATGAPAPRR
ARRTPINPPP FPPAAAVPTA RGALSVLHVA GPRFGRGVIE PGAPVTPGEL QEHLMGDLTL
LMNDGVPRPD LLVVAGNLTE SGSPREFSDA LSFLTGLRVL LGLEPHRLVV VPGPRDVTMA
ASRAYFATCE ADDVDPQPPY WPKWRHYARL FDELYQGLED RIFDSEQPWT LFPVPDLRVV
VAGLNSTVAI THREEDRYGF LGEAQSTWFA QRLRHYQQSG WLRLGAMAHA PGPRTPYADE
VAVPDRASLR DRGSFNRLVG PMLNLLLADA APGARVDPVV PLATASRDGR AQVLRLDAGG
MTRWVLGRDD RHEVGEPTSL SWPRAEATFG AAGPAQVPDP RRPAVVEGPT QGEAVDPPAA
APAVAPPAPL ERLLDRLAEV CEARHDRVLL RRVEADPPHL YVTYRADGVV RQQRVGAYVG
TPAPADVDHF ARRVHATDPD IPSELVYDGD RVPRGLAEAA QRRGVRLLHL TEFQGLLDLR
EYVAAQTARL QADRLYPPGQ YVPQRYRHLV GADQRVREDV VDELLELISA PDGRFVLVLG
DFGRGKTFAL REVARRLPTA APDLIPILVE LRALDKAHSV DGLVAAHLAN HGEQVIDLKA
FRYMLRQGRI VLLFDGFDEL VARVTYDRAA DHLETLLQAA EGHAKIVVSS RTQHFKTNSQ
VLTALGERVG LLPHRRVLAI EDFTPGQIET FLRNRYGGDE RAARERLDLL AGVKDLLGLS
RNPRMLGFIA NLDEGRLAAV AGAGGTFSAA ALYREILESW LDFEERRTQG IPGAPVSLRR
PELWHAVSRL AFQLWESGES YLRLAELAEA AGQLAGLADS RLSGPQAIHA VGAGSLLVRT
DDGLFGFIHT SVMEWLVAEG IAAQLNRGEE PTALAVRPLS ALTVEFLGDL ADPARCTAWT
ARVLGDETAG ETVRANALRL SARLRLPDRA DLRGAVLRGE DLSHRELAGA DLTGADLTDT
RLVATNLTEA RLEHARLRGA RLDQARLAGA DLRDAELAGA RLFRADLRGA RITGSRWHRT
ALIDVSADAA LLRAPELRGA VVAPGRPVAP GLAPPAVGVA YGFEVGRLPV PVAYSPDGAV
LAVGSDDGGV LICDTAAGLP VRTLQGHRGR VYAVRFDAAS HQLVTGAADL TVRLWDADHG
DVRHVIEDVF AGWVWPLLTD GERGRLVVGD AAGVVRLYDT RTARLRHEWP GHAAPIWGTS
FSPDGRRVVV VDSAGVVRGW DIPSGRLAFE VREPEVVYRV VHSPDGRLLA AVGQHGRVWI
RRATDGELLR QPRGHEADVY ALDIHPDGTL MATGDTHGAL RLWEVETGRP VRVLGRQRGA
IYSVRFNGDG SLLATAASDG AIQLWDSADG QLRHDLTRHR GSVWPVVWRP DQAQVATSSN
DGTTRLWDVR TGQLQHTLRG HGRRVTALSF RDDGEVLAAC GNDGVVRLWE PRTGRLVRQL
ASPADRLLSA VFCPGESLVA APSGDGGVHL WNTDTGVDER ELNVDTDHVW ATAFSPDGDA
LATANDDDTV RLWYRRTGRH FATLTPHRGR VRAMAFSPDG ETIATGCDDQ LVRLWDAATA
TCRLTLEHHT DRVYAVSFNT DGTLLASASN DGVAVVWDAL TGERRTTLTE HTGRLWSCAF
SPNGNLLATA GDDLVIRLWD PGTGRLHGTL AAHTRRVWSV AFSPDSSLLA SAGDDGTVRL
WDVADPEHAQ LRTTLIGLPD GWAAVSPDGR YKLDGDPGGQ FWHVIGTCRF EVGELDPYLT
QVRRLAVDAP F
//
