ID A0A1C6UKL2_9ACTN Unreviewed; 543 AA.
AC A0A1C6UKL2;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:SCL54518.1};
GN ORFNames=GA0070603_1819 {ECO:0000313|EMBL:SCL54518.1};
OS Micromonospora chersina.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47854 {ECO:0000313|EMBL:SCL54518.1, ECO:0000313|Proteomes:UP000198605};
RN [1] {ECO:0000313|EMBL:SCL54518.1, ECO:0000313|Proteomes:UP000198605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44151 {ECO:0000313|EMBL:SCL54518.1,
RC ECO:0000313|Proteomes:UP000198605};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
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DR EMBL; FMIB01000002; SCL54518.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C6UKL2; -.
DR STRING; 47854.GA0070603_1819; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000198605; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR021938; DUF3553.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF12073; DUF3553; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SCL54518.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 31..202
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 226..384
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 543 AA; 59438 MW; 6F3696D9D21E15CC CRC64;
MRLTTHSTTL RRAAKSLFGW TALRPNQLAA MRAVMKRRDA LVVLPTGAGK SAIYQIPASL
IPGPTVVISP LLALQQDQIA ALNERQRPEL RAVRISSDET AAQQAEAIEE IRAGRAEFLF
ITPEALSNPD RLAEVRGLKP ALVAIDEAHC ISAWGHDFRP DYLALGHLIE GIGRPPVVAL
TATASPPVRD DIIARLRLRE PEVVVSGLDR PNLFLEVAHC PTDDYRWRRL VALLRDDERP
GIIYVPTRRA AEELAQRLTD AGFPAEYYHG GMPTGARNDL HEAFLADQVP IMVATSAFGM
GIDKPNIAWV VHMALPDSPD SYFQEIGRAG RDGAPARVLL LWRAEDVGLQ RYFSGGLPDE
KELAELAALL RKQARTKKEL RELTGLGPRK LGQYVSLLEQ VGAAEPRARQ RIAAPRYAPA
AAESGRAALA EAERQQTVTR SRTDMMRAFA ETTGCRGQAL LAYFGEQMSV VCGHCDNCHA
GTSVAGDGAV GPFPVHSQVR HPEWGAGLVL SYEEDKMTVL FDEVGYKTLS VRVVSEQGLL
ELD
//
