ID A0A1C6UNM8_9ACTN Unreviewed; 1006 AA.
AC A0A1C6UNM8;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:SCL55631.1};
GN ORFNames=GA0070617_3012 {ECO:0000313|EMBL:SCL55631.1};
OS Micromonospora yangpuensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=683228 {ECO:0000313|EMBL:SCL55631.1, ECO:0000313|Proteomes:UP000198937};
RN [1] {ECO:0000313|EMBL:SCL55631.1, ECO:0000313|Proteomes:UP000198937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45577 {ECO:0000313|EMBL:SCL55631.1,
RC ECO:0000313|Proteomes:UP000198937};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; FMIA01000002; SCL55631.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C6UNM8; -.
DR STRING; 683228.GA0070617_3012; -.
DR OrthoDB; 7628974at2; -.
DR Proteomes; UP000198937; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:SCL55631.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198937};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 29..105
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|SMART:SM00862"
FT DOMAIN 112..256
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT DOMAIN 323..458
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REPEAT 909..942
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 1006 AA; 109711 MW; DE0BE3F34055D263 CRC64;
MPDSFTARPA ATTGIMFRVL GPLQVEGPAG TVRIPPGRQE IILACLLMEA GRVVATDRLL
DLIWHEEPPD TARTQIQICV SRIRKSFTAA GLSASVVSRA PGYLLRTDED TVDLHVFNRQ
VTAARVLVKE GRLAEAAESL RAAVALWRGP CLSGIPSEAL RTRGLRLDED RLTAIETYLE
LELGLGRSHE IVGEASRLVH EYPLRERLRG QLMLALYRSG RQAEALDVYR AGRELLAEEL
GLAPGEELRQ LEGAILAGDP AALHATGAPA PEPVRPPVAS VHPTPYGEER PHQLPADTAD
FVTSEPLVRS LERALLGDDG QRALGVVVIA GKPGIGKSAL GTHLAHRLGG ERFPDGQLYC
DLRGAGTEPV STKDALGRFL RALGIPGPVI PDDTDERAEM YRTLLATRRM LVVLDDAASE
RQISPLLPGS SSCAVLVTSR SRLTALPGAH RVELDVLDQT QALDLLGRVI GTERVEREPE
AAAALVRTVG GLPLALRIVA ARLAARPHWT LASMVHRLAN ERHRLDELAH GEMTMRASLS
LTHDGLNRAD RRLLRLFSLA QGPTVPGWIA GALLDDHRPI PSDLVEPLVD VQMLDAVAVE
STGEFRYRFH EVIRLFAREQ LALNDSPAVQ LAATERMIGG WLAITEQAHA RVYGGDFTVL
RGTAARWSPP TDYVDGLLTD PIEWLDSEQA NLCLAVDQAA QAGLDELCWD LATTLVTLFE
ARGYFDHWER THQRALQVTR AADNRRGTAA VLSSLGTLHI SRQQPDQARR SLSAAQETFD
ELGDLHGLAL CRRDLALLER QGGDDDRALV LYEHAARDFE RVGDIVGRAT VLTQSAHIWM
RRGHSAVAQA QLEESLEIFR SVGYSRGEAH ALRRAGQVLL QRGEHAQAEQ TLAGVLTMVR
RSGDIIGEGH LLRNLGEVHA ATGRYEQARG AFERALAVRE QIMDHGGAAA VRLDLARLMA
RAGARGRAGE LLENAVATFR ERGMRHELRE AERLLGEIAA SRPAAS
//
