ID   A0A1C6UZS7_9ACTN        Unreviewed;       333 AA.
AC   A0A1C6UZS7;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=GA0070617_4107 {ECO:0000313|EMBL:SCL59457.1};
OS   Micromonospora yangpuensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=683228 {ECO:0000313|EMBL:SCL59457.1, ECO:0000313|Proteomes:UP000198937};
RN   [1] {ECO:0000313|EMBL:SCL59457.1, ECO:0000313|Proteomes:UP000198937}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45577 {ECO:0000313|EMBL:SCL59457.1,
RC   ECO:0000313|Proteomes:UP000198937};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMIA01000002; SCL59457.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C6UZS7; -.
DR   STRING; 683228.GA0070617_4107; -.
DR   OrthoDB; 9805663at2; -.
DR   Proteomes; UP000198937; Unassembled WGS sequence.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198937}.
FT   DOMAIN          19..331
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   333 AA;  35167 MW;  8A4C87EAB191EA69 CRC64;
     MSTVNREIHL ASRPTGWPTA ENFRLVETPV PTPGPGQIVV RNRFVSVDPY MRGRMNDVRS
     YVPPFQLDAP LDGGAVGEVV ASEADGFTPG DVVLHGLGWR EYALLDATAA RTVDPDLAPL
     TAYLSVLGMT GLTAYAGLLE VAGMAEGETV FVSAAAGSVG SLVGQIAKLK GAGRVVGSAG
     SAAKVDRLRE LGFDAAFDYH DGPVGDSLRA AAPDGIDVYF DNVGGDHLEA AISSMRLHGR
     AAICGMIAQY NDTEPPAAPR NLAQVIGKRL TLRGFLVGDH GHLRERFVGE MAGWLRDGSL
     SYDETIVDGL DNAPEAFLGL LRGENLGKML VRV
//