ID   A0A1C6VHD9_9ACTN        Unreviewed;       614 AA.
AC   A0A1C6VHD9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Vancomycin resistance protein YoaR, contains peptidoglycan-binding and VanW domains {ECO:0000313|EMBL:SCL65300.1};
GN   ORFNames=GA0070617_5721 {ECO:0000313|EMBL:SCL65300.1};
OS   Micromonospora yangpuensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=683228 {ECO:0000313|EMBL:SCL65300.1, ECO:0000313|Proteomes:UP000198937};
RN   [1] {ECO:0000313|EMBL:SCL65300.1, ECO:0000313|Proteomes:UP000198937}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45577 {ECO:0000313|EMBL:SCL65300.1,
RC   ECO:0000313|Proteomes:UP000198937};
RA   Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMIA01000002; SCL65300.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C6VHD9; -.
DR   STRING; 683228.GA0070617_5721; -.
DR   Proteomes; UP000198937; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007391; Vancomycin_resist_VanW.
DR   InterPro; IPR022029; YoaR-like_PG-bd.
DR   PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR   Pfam; PF12229; PG_binding_4; 1.
DR   Pfam; PF04294; VanW; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198937};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          249..368
FT                   /note="YoaR-like putative peptidoglycan binding"
FT                   /evidence="ECO:0000259|Pfam:PF12229"
FT   REGION          34..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   614 AA;  65530 MW;  1C4BDF05532B428F CRC64;
     MWYVPIEVPL TLYGEKTPPA DDRPTVQVTA VSWPGVDPPP TQAGPPTAGP AGRRSRFRRP
     RVLLAAGVTT VVLAGAGAYA YAGDVPRGTT VLGTEVGGRS RTAAAGELRA ELERRTGTLT
     APLTVRVGEK TAEIDPAEVG LTVDVDATVA AAAEAGAHPV SRLVGSREVE PVVVVDADRL
     DAALRKVMGN QGRKMTMPAI SFKGTTVKVT RPKPSLALDP QRSAEAVRAG WLAGQPVTVP
     LVETHPATTA EEVDKLAAEL AEPAVAKAVT LRTDQGSVSI PPAAIAKSLR FSADKAGKLT
     PKVDVKRLRS ALGDKLSKIE VEARDARMAV TGGKPKVVDD GRPGQQLDTA TLGKDLLAVL
     PKGDDRTVSG ELKPVQPEVT ADKIGELGIK ERVSKFTTQF TGGLSAPRSK NIVQIAKDVD
     GTVVLPGETF SLNGHTGERG YAQGYHDAPV IMDGKLVPGV GGGTSQFTTT LFNATYYAGL
     EDVEHKPHSY WFSRYPAVIE STIFWPNLDF KFRNNTEYGV LIDTSYTSSS ITVSIWSTKI
     YDSVKTEYGP RRDITKPVTT YLEPGPSCIP ANGIDGFAQD AFRVIKKDGK VVKREKFSWR
     YAAEPRFVCG KKPS
//