ID A0A1C7GRL7_9FIRM Unreviewed; 511 AA.
AC A0A1C7GRL7;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 2.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN ORFNames=A4V00_09750 {ECO:0000313|EMBL:ANU54280.2};
OS Hungateiclostridiaceae bacterium KB18.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX NCBI_TaxID=1834198 {ECO:0000313|EMBL:ANU54280.2, ECO:0000313|Proteomes:UP000092525};
RN [1] {ECO:0000313|Proteomes:UP000092525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KB18 {ECO:0000313|Proteomes:UP000092525};
RA Uchimura Y., Wyss M., Brugiroux S., Limenitakis J.P., Stecher B.,
RA McCoy K.D., Macpherson A.J.;
RT "Complete Genome Sequences of Twelve Strains of a Stable Defined Moderately
RT Diverse Mouse Microbiota 2 (sDMDMm2).";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
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DR EMBL; CP015400; ANU54280.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7GRL7; -.
DR STRING; 1834198.A4V00_09750; -.
DR KEGG; ruk:A4V00_09750; -.
DR OrthoDB; 9803205at2; -.
DR Proteomes; UP000092525; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000092525};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}.
FT DOMAIN 327..420
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 69..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 511 AA; 57151 MW; A76A95F8FF896185 CRC64;
MVIAVLAAAL AGAAAFFLGI NYRKSKAEAA IGSAEEEAKR IVGDAIKTAE ARKKEIILEG
KDEIHKLRNE SEKELSDRRR EIQHQERRNL QKEESLEKKL ETLERKEDQI DQRNKKAEER
LKEAEAVRKS QFDMLEKISS FSMEQAKEYL LNNLENELVH EKAVKIREFE QQLKEDSDNA
AREIIATAIQ RCAADHVSEA AISVVPLPND EMKGRIIGRE GRNIRAIETL TGVDLIIDDT
PEAITLSSFE PVRREVARVA LEKLISDGRI HPTRIEETVE KARREVESAI KQAGERAVLE
VGVNGVHHEL VKLLGRLRFR TSYGQNVLNH SLEVAYLSGM IASELGLNPT VAKRAGLLHD
IGKALDHEME GSHVQIGVEV AKKYRENEAV VHAIAAHHGD VEAKTIVACI VQAADAISAA
RPGARRENLE NYIKRLEKLE ELVSSFGGVD SCYAIQAGRE VRILVKPDLV SDEEMTLLAR
EICKKIEGDL DYPGQIKVNM IRESRAVDYA K
//
