ID   A0A1C7GU70_9FIRM        Unreviewed;       812 AA.
AC   A0A1C7GU70;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 2.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE            Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE   AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN   ORFNames=A4V00_14865 {ECO:0000313|EMBL:ANU55190.2};
OS   Hungateiclostridiaceae bacterium KB18.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX   NCBI_TaxID=1834198 {ECO:0000313|EMBL:ANU55190.2, ECO:0000313|Proteomes:UP000092525};
RN   [1] {ECO:0000313|Proteomes:UP000092525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KB18 {ECO:0000313|Proteomes:UP000092525};
RA   Uchimura Y., Wyss M., Brugiroux S., Limenitakis J.P., Stecher B.,
RA   McCoy K.D., Macpherson A.J.;
RT   "Complete Genome Sequences of Twelve Strains of a Stable Defined Moderately
RT   Diverse Mouse Microbiota 2 (sDMDMm2).";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end. {ECO:0000256|RuleBase:RU362066}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC       ECO:0000256|RuleBase:RU362066}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC       Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC       ECO:0000256|RuleBase:RU362066}.
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DR   EMBL; CP015400; ANU55190.2; -; Genomic_DNA.
DR   RefSeq; WP_066539663.1; NZ_CP021422.1.
DR   AlphaFoldDB; A0A1C7GU70; -.
DR   STRING; 1834198.A4V00_14865; -.
DR   GeneID; 83336386; -.
DR   KEGG; ruk:A4V00_14865; -.
DR   OrthoDB; 9776025at2; -.
DR   Proteomes; UP000092525; Chromosome.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR   PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW   ECO:0000256|RuleBase:RU362066};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092525};
KW   Secreted {ECO:0000256|RuleBase:RU362066}.
FT   DOMAIN          29..131
FT                   /note="Flagellar hook-associated protein 2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02465"
FT   DOMAIN          523..801
FT                   /note="Flagellar hook-associated protein 2 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07195"
SQ   SEQUENCE   812 AA;  86857 MW;  43CF96EE2F5EB7EE CRC64;
     MASVTSLMNS TSSTSSLYGN RNVISGLASG MDTEAMIENS VAGYKTKISS LQQKMTQMQW
     KQDAYRSLIT QMNNLLNKYT SYTSSTNLFS SSFFSKAINT VANGANAAKV SATGKSSSNV
     SIDAIKQLAE AASYTVGTNH LVDKGSDTSK IEWNKNVETS KVAGSITLEY GGGDKKSGST
     IRLSFGEDEV FNSAQEMADA INAKLKEAKI TTSSGSNSAD NYLEASVDAT GRVVINDKKN
     NNFRITGVSG EGMEKIFEET ERGSLAVSKA PVKKADLVDS VGREEYLKDQ TIYVNLDGKT
     KSIKLEDIFN SDTYKNTAKG TEQEKSEAFA TALNERLNSE FNGKVKVEAN ADGSLKFTGP
     ENNGSTLTIK GGSDAVNNAL GLGEGGYSTT LQTSWTLKKV LGDSAAGLFT EAATNADGDY
     VDSADKAAKV ATIEINGTKL QFGEDDTIQT VMDKINGSDA GVELKYSSMT GNFAFTAKET
     GADSKIDIGG TLGTALFGRV DSSQIADDKA EVNPDIKGTY TKGKDAEFVA TVNGERLELT
     RSSNTVDLDG LSVTLKGTFD EGSEKITFTT TSDSDKIVDT VKAFVEDYNK LVTELHNAYS
     TMPLQDSKGN DYLPLTEDEI SKNSESYIKS YEEKAKTGLL FGDSDLSNLY TRLTQSVQSS
     GEIGAALRSI GLSVEYSSSN GLSTLNLDEE KLRSALDSDP DKVKNAFTAS TSTGASSNGI
     MAGLKSTLEM YGKTSIGSPG ILVKKAGTTL SSYSLSDNEI QDKIDSLQKQ IDKWQDKMSD
     RIDFYTNQFT RLEMLINQMN SQSSALSGMM GG
//