ID A0A1C7GUH8_9FIRM Unreviewed; 275 AA.
AC A0A1C7GUH8;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:ANU55995.1};
GN ORFNames=A4V00_04475 {ECO:0000313|EMBL:ANU55995.1};
OS Hungateiclostridiaceae bacterium KB18.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX NCBI_TaxID=1834198 {ECO:0000313|EMBL:ANU55995.1, ECO:0000313|Proteomes:UP000092525};
RN [1] {ECO:0000313|Proteomes:UP000092525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KB18 {ECO:0000313|Proteomes:UP000092525};
RA Uchimura Y., Wyss M., Brugiroux S., Limenitakis J.P., Stecher B.,
RA McCoy K.D., Macpherson A.J.;
RT "Complete Genome Sequences of Twelve Strains of a Stable Defined Moderately
RT Diverse Mouse Microbiota 2 (sDMDMm2).";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP015400; ANU55995.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7GUH8; -.
DR STRING; 1834198.A4V00_04475; -.
DR KEGG; ruk:A4V00_04475; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000092525; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000092525}.
FT DOMAIN 1..275
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 275 AA; 29684 MW; 74BD6BA1CDC265FE CRC64;
MKIIIVGLGL IGGSIAKALK QNTPHQVLGM DTDEGSLLDA CSCGAIDGKA GIEDLKNADM
VYLCVYPGAA LDFTREHGPD LREGCVLTDT CGIKSAVCAG MEELRNTGRY VFVAGHPMAG
KERSGFAASD PSIFVGASYL LVPGDAPGWA VELVEEMALC MGFGRTVRTD PKHHDQMIAF
TSQVPHALAC AYVLSPRCPE HKGFSAGSYR DVSRVANIND ELWSRLFLDN KDALTEELEE
LMGNLKAIRD AVSKGDEREL RKLLKRAGDI KRRVG
//
