ID A0A1C7GYL2_9BACE Unreviewed; 257 AA.
AC A0A1C7GYL2; A0A4S2DHV7;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Prephenate dehydratase {ECO:0000313|EMBL:ANU56427.1};
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:NDO58577.1};
GN ORFNames=A4V03_01625 {ECO:0000313|EMBL:ANU56427.1}, E5353_02440
GN {ECO:0000313|EMBL:TGY40541.1}, FMM78_01880
GN {ECO:0000313|EMBL:NDO58577.1};
OS Bacteroides caecimuris.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1796613 {ECO:0000313|EMBL:ANU56427.1, ECO:0000313|Proteomes:UP000092631};
RN [1] {ECO:0000313|Proteomes:UP000092631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I48 {ECO:0000313|Proteomes:UP000092631};
RA Uchimura Y., Wyss M., Brugiroux S., Limenitakis J.P., Stecher B.,
RA McCoy K.D., Macpherson A.J.;
RT "Complete Genome Sequences of Twelve Strains of a Stable Defined Moderately
RT Diverse Mouse Microbiota 2 (sDMDMm2).";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ANU56427.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I48 {ECO:0000313|EMBL:ANU56427.1};
RA Uchimura Y., Wyss M., Brugiroux S., Limenitakis J.P., Stecher B.,
RA McCoy K.D., Macpherson A.J.;
RT "Complete Genome Sequences of Twelve Strains of a Stable Defined Moderately
RT Diverse Mouse Microbiota 2 (sDMDMm2).";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:TGY40541.1, ECO:0000313|Proteomes:UP000309566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NM63_1-25 {ECO:0000313|EMBL:TGY40541.1,
RC ECO:0000313|Proteomes:UP000309566};
RA Navarre W., Wong E., Huang K., Tropini C., Ng K., Yu B.;
RT "Microbes associate with the intestines of laboratory mice.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:NDO58577.1, ECO:0000313|Proteomes:UP000589339}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD237 {ECO:0000313|EMBL:NDO58577.1,
RC ECO:0000313|Proteomes:UP000589339};
RA Elie C., Mathieu A., Saliou A., Darnaud M., Leulier F., Tamellini A.;
RT "Draft genome sequences of 15 bacterial species constituting the stable
RT defined intestinal microbiota of the GM15 gnotobiotic mouse model.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP015401; ANU56427.1; -; Genomic_DNA.
DR EMBL; VIRD01000009; NDO58577.1; -; Genomic_DNA.
DR EMBL; SRYX01000005; TGY40541.1; -; Genomic_DNA.
DR RefSeq; WP_065537699.1; NZ_VIRD01000009.1.
DR AlphaFoldDB; A0A1C7GYL2; -.
DR STRING; 1796613.A4V03_01625; -.
DR GeneID; 82185832; -.
DR KEGG; bcae:A4V03_01625; -.
DR OrthoDB; 1522519at2; -.
DR Proteomes; UP000092631; Chromosome.
DR Proteomes; UP000309566; Unassembled WGS sequence.
DR Proteomes; UP000589339; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000092631}.
FT DOMAIN 1..257
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 257 AA; 29425 MW; EE0B2EA87F710A5B CRC64;
MRILILGAGK MGSFFTDILS FQHETAVFDV NPHQLRFVYN TYRFTTLEEI KDFEPELVIN
AVTVKYTLDA FHKVLPVLPK DCIISDIASV KTGLKKFYEE SGFRYVSSHP MFGPTFASLS
NLSNENAIII SEGDHLGKIF FKDLYQTLRL NIFEYTFDEH DETVAYSLSI PFVSTFVFAA
VMKHQEAPGT TFKKHMAIAK GLLSEDDYLL QEILFNPRTP GQVANIRTEL KNLLEIIENK
DAEGMKKYLT KIREKIK
//
