ID A0A1C7H786_9BACE Unreviewed; 1524 AA.
AC A0A1C7H786;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A4V03_02155 {ECO:0000313|EMBL:ANU59630.1};
OS Bacteroides caecimuris.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1796613 {ECO:0000313|EMBL:ANU59630.1, ECO:0000313|Proteomes:UP000092631};
RN [1] {ECO:0000313|Proteomes:UP000092631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I48 {ECO:0000313|Proteomes:UP000092631};
RA Uchimura Y., Wyss M., Brugiroux S., Limenitakis J.P., Stecher B.,
RA McCoy K.D., Macpherson A.J.;
RT "Complete Genome Sequences of Twelve Strains of a Stable Defined Moderately
RT Diverse Mouse Microbiota 2 (sDMDMm2).";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP015401; ANU59630.1; -; Genomic_DNA.
DR RefSeq; WP_065540242.1; NZ_NHMU01000002.1.
DR GeneID; 82185932; -.
DR KEGG; bcae:A4V03_02155; -.
DR Proteomes; UP000092631; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00146; PKD; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 4.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 3.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Kinase {ECO:0000313|EMBL:ANU59630.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000092631};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:ANU59630.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1524
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008887109"
FT TRANSMEM 912..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 958..1175
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1236..1351
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1422..1521
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT REGION 1392..1415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1398..1413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1284
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1524 AA; 174493 MW; 1330B7C42D14C283 CRC64;
MMKKTLISII LLLAIAFSTY AQQHCFFTHY STEDGLSQNT VMNILQDHKD NLWFATWDGI
NRFNGYTFKT YKARQRNYIS LTNNRVDRMY EDRYGFLWLL TYDNRVHRFD PKTETFEQVP
AAGEEGSAFN VHTIEVMPNG TVWLLTENDG AIRILTHPDE NNRLTWDIYS SKTELFPSLH
VFKVHQDKAG NDWLLTDNGL GIIRPGKKEP NSYFTETKGK FGGMNQAFYA VQERDKDICF
ASDHGRIWSY QKESGEFTLI ELPTKGQITS IHPIAPDVSV ITTDSDGFFT YNLRTKTNVH
YSFLTCKALP AKPILSAYVD RSSEVWFEQE EPGVVAHFNP STGVVTREQI PIEYSNPERS
RPAFHIHEDV NGYLWVHPYG GGFSYFDPQK KCLVPFYNGL GSRDWRFSNK IHSAFSDKQG
NLWLCTHSKG LEKVTYRNVP FTMIIPMPHE HESLHNEVRA LCEDKLGNLW VGLKDGILRI
YDADKTYKGY LTENGTISAT GTPMPGTVYH VIQDSKGIIW IATKGDGLVR AEPTSSNGMS
YKLTRYLHRE DDMYSLSDNN VYCIYEDHYG RIWLATFAGG INYITKNEAG KTLFINHRNN
LKGYPIDPCY KARFITSDNN GRLWVGTTTG AVAFDENFKK PEDVKFYHFS RMPNDTQSLS
NNDVHWIIST KKKELYLATF GGGLNKLVSI SKNGHGEFKS YCVLDGLPSD VLLSIREDSK
QNLWISTENG ICKFIPSEER FESYDERSIT FPVRFSEAAS ALTAKGSMLF GASGGVFIFN
PDSIRKSSYI PPIVFSKLTV ANEDITPGGN SLLKVDIDDA DKLVLSHKEN IFSVHFAALD
YTNPQNIQYA YILDGFEKQW TFADKQRSVT YTNLPKGEYV LRVRSTNSDG VWVDNERILD
IVILPSFWET PIAYVLYILF ILIIILVAVY ILFTIYRLKH EVSVEQQISD IKLRFFTNIS
HELRTPLTLI AGPVEQVLKN DKLPADAREQ LVVVERNTSR MLRLVNQILD FRKIQNKKMK
MQVQRVDIVP FVRKVMDNFE AVAEEHRIDF LFQTEKEHLY LWVDADKLEK IVFNLLSNAF
KYTPNGKMIT MFIREDENTV SIGVQDQGIG IAENKKKSLF VRFENLVDKN LFNQASTGIG
LSLVKELVEM HKATISVDSR LGEGSCFKVD FLKGKEHYDK ETEFILEDAD APVRMGQVVD
IANSSIQSET LIPDDSEKIE AVYEEDAAKE ENSKELMLLV EDNQELREFL RSIFSPMYRV
VEAADGREGA NKALKYLPDI IISDVMMPEK DGIEMTRELR ADMTTSHIPI ILLTAKTTIE
SKLEGLEYGA DDYITKPFSA TYLQARVENL LMQRKKLQSF YRDSLMHINM SVTSGELVAL
TKAMAEEERK IVPEREEEQT QLQSQQQPTI PDMSPNDRKF MDKLVELMEQ NMDNGDLVVD
DLVRELAVSR SVFFKKLKTL TGLAPIEFIK EIRIKRATQL IETGEFNMTQ ISYMVGINDP
RYFSKCFKAQ VGMTPTEYKE KIGR
//
