ID   A0A1C7LXD1_GRIFR        Unreviewed;       986 AA.
AC   A0A1C7LXD1;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Rab guanine nucleotide exchange factor SEC2 {ECO:0000313|EMBL:OBZ67464.1};
GN   Name=SEC2 {ECO:0000313|EMBL:OBZ67464.1};
GN   ORFNames=A0H81_12645 {ECO:0000313|EMBL:OBZ67464.1};
OS   Grifola frondosa (Maitake) (Polyporus frondosus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Grifolaceae; Grifola.
OX   NCBI_TaxID=5627 {ECO:0000313|EMBL:OBZ67464.1, ECO:0000313|Proteomes:UP000092993};
RN   [1] {ECO:0000313|EMBL:OBZ67464.1, ECO:0000313|Proteomes:UP000092993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9006-11 {ECO:0000313|EMBL:OBZ67464.1,
RC   ECO:0000313|Proteomes:UP000092993};
RA   Min B., Park H., Kim J.-G., Cho H., Oh Y.-L., Kong W.-S., Choi I.-G.;
RT   "Whole genome sequencing of Grifola frondosa 9006-11.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBZ67464.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LUGG01000024; OBZ67464.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C7LXD1; -.
DR   STRING; 5627.A0A1C7LXD1; -.
DR   OMA; REDMFWA; -.
DR   OrthoDB; 1357504at2759; -.
DR   Proteomes; UP000092993; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd21044; Rab11BD_RAB3IP_like; 1.
DR   Gene3D; 6.10.140.910; -; 1.
DR   InterPro; IPR040351; RAB3IL/RAB3IP/Sec2.
DR   InterPro; IPR009449; Sec2_N.
DR   PANTHER; PTHR14430:SF0; RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR SEC2; 1.
DR   PANTHER; PTHR14430; RABIN3-RELATED; 1.
DR   Pfam; PF06428; Sec2p; 1.
DR   SUPFAM; SSF144284; Sec2 N-terminal region; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092993}.
FT   DOMAIN          144..219
FT                   /note="GDP/GTP exchange factor Sec2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06428"
FT   REGION          373..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          516..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          687..901
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          193..234
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        537..551
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        577..592
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        594..623
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        730..751
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        841..872
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   986 AA;  106394 MW;  31D4EB940F932EA7 CRC64;
     MDRPLTPDDI NATKLAGTKL DLKRHGADLA WSDAICINGE DAKLQRHNSD PDAEAMVIGS
     LRSQIEDLIS QVSQLNNKLV TSYNRVSNLE DTLHVTSESL RASELKVSQL ELERTQHLSA
     LSTGLLVEKS HVTNELTRLM ERATEEAARR GQAESARAEI EKDLDDLSAG LFNQANTMVA
     QARIGEARSA RKLQETEIAL KGAEEVVGVL QEQMQALQEQ KELADRRVEE MRVTMGKGKW
     VDRVPDKSRS NALRLMCIHP PYQEFILFVS HLRSIRPAAP QPPAMSTLLP LPFLARLVTE
     DSDPTVRLDL APSLNWLSRR SVLAAIHSGQ LTVEPMHTAA LLEELAPSAI PGNSHNTNIL
     CALCGVPIFP PTSNESPSST PVSPSPNSMS RTSTQGNSWS SSLFKNSLVQ TISTATPSNL
     TLTSTFHRHH TQLSSSPIPL EPPTQVYIFR LDATSSGLPV SLPLSSQQPG TPTRQSTIYP
     LCGSGWCLAR LRTTCSLWAF VRTSVVEKVW EEALYTPPPS GIPTKAGLNG IEKRDSANSA
     SDIDKKPTLP PRKSKIGALW GSMQRTLSST KELEKPAANP VDSEKVEPPP RRDSILRSLP
     PPPLHPSLSS SAPKAPSAVP PPLPKRNRDR DAKPLSRSST PDAAQKLTVD GASTEAIVQP
     DEQPHTEISV ETVADALDQP LDEAPHTEIR VETSTDALAQ PPIPLTRDNS HDDFATPIEE
     LATFPNTPRP STPSIVPLPP SSPPTPEPGY VSTPPETASV VDGLPPSASP TPPIATLHPE
     EEKAPSRTVS PVPPPLPRRA AARSARRMSV AAPAAPTLST ATVDAVPAPV REEDESGETT
     AESSDPALAA PTEQTPAVEQ LSESQVSPEE AQGDDSPPQY EEGQDTTKSN ENLHATDEKQ
     LLGASIEVEG ASLVAPSING IKDGVQGRPE SVHAGPETNG ILEEVDSVAE VDYAGYVGDS
     TWEERTWKEL VRLREEMFWA RIGGVH
//