ID A0A1C7LYY9_GRIFR Unreviewed; 306 AA.
AC A0A1C7LYY9;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Uncharacterized protein C9.08c {ECO:0000313|EMBL:OBZ69933.1};
GN Name=SPAC9.08c {ECO:0000313|EMBL:OBZ69933.1};
GN ORFNames=A0H81_10393 {ECO:0000313|EMBL:OBZ69933.1};
OS Grifola frondosa (Maitake) (Polyporus frondosus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Grifolaceae; Grifola.
OX NCBI_TaxID=5627 {ECO:0000313|EMBL:OBZ69933.1, ECO:0000313|Proteomes:UP000092993};
RN [1] {ECO:0000313|EMBL:OBZ69933.1, ECO:0000313|Proteomes:UP000092993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9006-11 {ECO:0000313|EMBL:OBZ69933.1,
RC ECO:0000313|Proteomes:UP000092993};
RA Min B., Park H., Kim J.-G., Cho H., Oh Y.-L., Kong W.-S., Choi I.-G.;
RT "Whole genome sequencing of Grifola frondosa 9006-11.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the steroid 5-alpha reductase family.
CC {ECO:0000256|ARBA:ARBA00007742}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ69933.1}.
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DR EMBL; LUGG01000015; OBZ69933.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7LYY9; -.
DR STRING; 5627.A0A1C7LYY9; -.
DR OMA; PHYALEW; -.
DR OrthoDB; 1364739at2759; -.
DR Proteomes; UP000092993; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 1.20.120.1630; -; 1.
DR InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR InterPro; IPR039357; SRD5A/TECR.
DR PANTHER; PTHR10556; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR PANTHER; PTHR10556:SF43; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2; 1.
DR Pfam; PF02544; Steroid_dh; 2.
DR PROSITE; PS50244; S5A_REDUCTASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092993};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 122..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 164..264
FT /note="Steroid 5-alpha reductase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50244"
SQ SEQUENCE 306 AA; 34446 MW; C51AB68DCEADF5E0 CRC64;
MMRSVQAQEC YDVARTWFAI IPPLLCPVSF LIDAPFGRFA PTERSILLFD GIKSWMVMEL
VSPITFVYTY LHSPLSPIYY GSAPPLSLSH PPTLLSTLYL FHYLNRAVVS PLRTPSRSKS
HIIVSLSAVF FNIVNGSLMG AYLSSPAAQS FLGDAFTRPL FWLGVGMWVA GFAGNILHDE
VLLNIRRSAK AKGKARAAAD SDDNNNGKNK NKQEHYAIPH GYLYSYISYP NYFCEWLEWL
GFALAAAPLP SFASAGQFLS TISPPYIFFL SEVLLMLPRA YKGHRWYHSR FPDYPPERKA
IIPFLL
//
