ID A0A1C7M3Q7_GRIFR Unreviewed; 524 AA.
AC A0A1C7M3Q7;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Guanine nucleotide-binding protein alpha-4 subunit {ECO:0000313|EMBL:OBZ71036.1};
GN Name=GPA4_0 {ECO:0000313|EMBL:OBZ71036.1};
GN ORFNames=A0H81_09481 {ECO:0000313|EMBL:OBZ71036.1};
OS Grifola frondosa (Maitake) (Polyporus frondosus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Grifolaceae; Grifola.
OX NCBI_TaxID=5627 {ECO:0000313|EMBL:OBZ71036.1, ECO:0000313|Proteomes:UP000092993};
RN [1] {ECO:0000313|EMBL:OBZ71036.1, ECO:0000313|Proteomes:UP000092993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9006-11 {ECO:0000313|EMBL:OBZ71036.1,
RC ECO:0000313|Proteomes:UP000092993};
RA Min B., Park H., Kim J.-G., Cho H., Oh Y.-L., Kong W.-S., Choi I.-G.;
RT "Whole genome sequencing of Grifola frondosa 9006-11.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ71036.1}.
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DR EMBL; LUGG01000013; OBZ71036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7M3Q7; -.
DR STRING; 5627.A0A1C7M3Q7; -.
DR OMA; WRPIVYF; -.
DR OrthoDB; 1864818at2759; -.
DR Proteomes; UP000092993; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000092993};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 171..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 57631 MW; AFC46783DDEEAA7B CRC64;
MRQSRLIDDA EALRISNAID EDLKICGSRK SSYHSMPPAF TLNSAYHANP GCCTYIAHPL
EHDVYRLIIR CGILAGFLWH IRICCAGQFA VSHPTYNASA TVMLLGQAES GKSTLQKQFQ
LYYSSQTLDH ERPSWRPIVY FNILKAIRMI LDELDYEYNL RPSDPLSVSV AASTSTSGSG
SSSSSHSRPD PSWFPELAQI RTKLLPLVAS EDALASELSG GITVSGGRTG VFVRAGWQAL
VTSGRSYALA ESHLASSSST RQSAVANIVA KTIAASSQEI EQLWHHPGVQ SLLRNNKLRL
EEYAAFFLAS IRRIAQPDYL PSTEDILHVR LQTIGVTEHT FDINMGGTHY NWLLYDVGGA
RHAWVPYFDD GMLRSAVVPA SRPLLLCVPS AFRSAARDET RFSRVICLAA LATAIIFLAP
ISAFDSVGLT EAEAAGRDQS SQIVRAAGAM LAGISSYGDR PNSYEEVSEY FRAHFIQVHK
RKDVSHRPLY LHFTSMLDIK ATQAIIINVG EAIMRLHLSK VGLA
//
