ID A0A1C7M8Q0_GRIFR Unreviewed; 684 AA.
AC A0A1C7M8Q0;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=prp43 {ECO:0000313|EMBL:OBZ72947.1};
GN ORFNames=A0H81_07022 {ECO:0000313|EMBL:OBZ72947.1};
OS Grifola frondosa (Maitake) (Polyporus frondosus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Grifolaceae; Grifola.
OX NCBI_TaxID=5627 {ECO:0000313|EMBL:OBZ72947.1, ECO:0000313|Proteomes:UP000092993};
RN [1] {ECO:0000313|EMBL:OBZ72947.1, ECO:0000313|Proteomes:UP000092993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9006-11 {ECO:0000313|EMBL:OBZ72947.1,
RC ECO:0000313|Proteomes:UP000092993};
RA Min B., Park H., Kim J.-G., Cho H., Oh Y.-L., Kong W.-S., Choi I.-G.;
RT "Whole genome sequencing of Grifola frondosa 9006-11.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ72947.1}.
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DR EMBL; LUGG01000007; OBZ72947.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7M8Q0; -.
DR STRING; 5627.A0A1C7M8Q0; -.
DR OMA; MKVYPLY; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000092993; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF109; ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:OBZ72947.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000313|EMBL:OBZ72947.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000313|EMBL:OBZ72947.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000092993}.
FT DOMAIN 46..194
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 191..364
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 629..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 496..527
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 635..661
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 77280 MW; 43A8388FE099F588 CRC64;
MSSERRSRKR WMEMSTPSPS SHFHQYKKIL EMRKKLPVFG QMDEFLKMFS KKQIIVMVGE
TGSGKTTQIP QFPRRVAAMS VAKRVADEMD VQLGKQVGYS IRFEDMTEPG TTFLKYMTDG
MLLREAMNDP DLARYSTIIL DEAHERTLAT DILMGLLKNL ARRRPDLKII VMSATLDAVK
FQKYYSIAGP GTMAPLFKVP GRTHPVEVFY TQQPEPDYVE AAIRTVLMIH RAEEPGDILL
FLTAHFRCSS AARKPGGPPG RKIVVSTNIA ETSLTIDGIV YVVDPGFSKQ KVYNPRIRVE
SLLVSPISKA SAQQRAGRAG RTRPGKCFRL YTEKDFMTEL EEQTHPEILR SNLANTVLEL
AKLGIKDLVR FDYVDAPAPE TLMRALELLN FLSALDDDGN LTALGSMMAD FPLDPQMAKM
LIVSPEFRCS NEILTIVAML SVPSVWLRPP NQRKEADAAK AILTVPGGDH LTLMNVYNNY
VNNMHDKSWA WNNYLSARAL QQANNVRAQL QRTMERYEIE LVSTQDERRL WQNVQTALVC
GFFMQVAHKE GEKGSYLTVK DNQVVALHPS CGLDTQPDWV IFNEFVLTTK PYIRTVTEVR
PEWLLQYATQ YYDLSTFPDG ETKRALQKVS NRLSGKVEKP PKKKTKVASD EYRETLKRSI
KADGSSGRGS PSGNEPAKKK SKTS
//
