ID   A0A1C7MZK4_9FUNG        Unreviewed;       435 AA.
AC   A0A1C7MZK4;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=type I protein arginine methyltransferase {ECO:0000256|ARBA:ARBA00011925};
DE            EC=2.1.1.319 {ECO:0000256|ARBA:ARBA00011925};
GN   Name=PRMT14 {ECO:0000313|EMBL:OBZ82277.1};
GN   ORFNames=A0J61_09675 {ECO:0000313|EMBL:OBZ82277.1};
OS   Choanephora cucurbitarum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC   Choanephora.
OX   NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ82277.1, ECO:0000313|Proteomes:UP000093000};
RN   [1] {ECO:0000313|EMBL:OBZ82277.1, ECO:0000313|Proteomes:UP000093000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ82277.1,
RC   ECO:0000313|Proteomes:UP000093000};
RA   Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT   "Choanephora cucurbitarum.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) +
CC         N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:48096, Rhea:RHEA-COMP:10532, Rhea:RHEA-
CC         COMP:11991, ChEBI:CHEBI:15378, ChEBI:CHEBI:29965, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:61897; EC=2.1.1.319;
CC         Evidence={ECO:0000256|ARBA:ARBA00001817};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBZ82277.1}.
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DR   EMBL; LUGH01000906; OBZ82277.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C7MZK4; -.
DR   STRING; 101091.A0A1C7MZK4; -.
DR   InParanoid; A0A1C7MZK4; -.
DR   OrthoDB; 197898at2759; -.
DR   Proteomes; UP000093000; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR11006:SF10; HISTONE-ARGININE METHYLTRANSFERASE CARMER-RELATED; 1.
DR   PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR   Pfam; PF06325; PrmA; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   4: Predicted;
KW   Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01015,
KW   ECO:0000313|EMBL:OBZ82277.1}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01015};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU01015,
KW   ECO:0000313|EMBL:OBZ82277.1}.
SQ   SEQUENCE   435 AA;  49452 MW;  DDA627AECB430179 CRC64;
     MSSEVPGVEH RDPQYFGYYA QLQHQQNMLQ DTVRTSTYRS SILLNGPKSF KDKLVMDVGA
     GSGILSYFAV QAGAKKVYAV EASGMANKMK KLVSAADTGK NAFLKDKVEV INAKIEDPNL
     PIPKVDTIIS EPIGVLLFHE RMLESYIYAR DHYLKEGGAL YPSKGNIYLA PFTDATLWSE
     TMAKARFWEQ TSFYGIDFSP LYKDARDEMF GMPVVGHFDP RSLITTPSLF DTYPVDFSTV
     TLNQLQDMTI PFSWPAQYTG LMHGVAGWFD LVFAPPPYDQ PNPEDLGTTI EMSTGPAAER
     THWQQVRFLF KEPLAVNAGQ KLRGWMRCIV NDMRSYTIFV EITASNSEVL SDPREINRET
     FATISTEDRP FVRRGVWELH EQTYNYNYTP GMMPDHKPEY SCLYEPEARL DQNAAYQNLD
     LASMNVMDDY EDFVN
//