ID   A0A1C7MZK8_9FUNG        Unreviewed;       632 AA.
AC   A0A1C7MZK8;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Hormone-sensitive lipase {ECO:0000313|EMBL:OBZ81866.1};
GN   Name=LIPE {ECO:0000313|EMBL:OBZ81866.1};
GN   ORFNames=A0J61_10085 {ECO:0000313|EMBL:OBZ81866.1};
OS   Choanephora cucurbitarum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC   Choanephora.
OX   NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ81866.1, ECO:0000313|Proteomes:UP000093000};
RN   [1] {ECO:0000313|EMBL:OBZ81866.1, ECO:0000313|Proteomes:UP000093000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ81866.1,
RC   ECO:0000313|Proteomes:UP000093000};
RA   Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT   "Choanephora cucurbitarum.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBZ81866.1}.
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DR   EMBL; LUGH01001026; OBZ81866.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C7MZK8; -.
DR   STRING; 101091.A0A1C7MZK8; -.
DR   InParanoid; A0A1C7MZK8; -.
DR   OrthoDB; 37251at2759; -.
DR   Proteomes; UP000093000; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   PANTHER; PTHR23025:SF3; HORMONE-SENSITIVE LIPASE; 1.
DR   PANTHER; PTHR23025; TRIACYLGLYCEROL LIPASE; 1.
DR   Pfam; PF07859; Abhydrolase_3; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        55..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        113..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          215..357
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
SQ   SEQUENCE   632 AA;  72584 MW;  359FAFE7F76EDB28 CRC64;
     MLDHLVGKPS PNFKRTQTIL TLIFGWYFIV YGKTRQLPRF IQQLNKKAGR SPWRIVLGSW
     LMFYLSQNIF LLVGLNAPDP LSRLYKRSFY RATWILTALD AGFFTAMPFK PTWVRHLLSI
     VFSAYYLVFA DAAEEKVRKT RATISIEQMR NSWEKGCHNP VLATISRFLR PTLILADILS
     VPRPDYHQDL PPVEVYRYYY SDRSKQFEEH DTILLQFPGG GFVSMPPPCH EDALYAWAKQ
     TELPVFSVNY RKAPEYPYPW PIEECFDFYV AIVESKGKVI GLKGDKDIRI ILVGDSAGGN
     VTAAVTLKIL AHNQQLAMQQ EQQQEEQQVS SILDGPITVP VGLVLIYPVL DFEMSCWMST
     SQLSLIRAES NTDLFRSSSL DSIWQTKDHL SHASPLSVVP DLEKKQSLWR RALGIKPSRQ
     KRVADRAHPI RDKIQTKDAW ATARLAMTSR MSFFNDRIIS PDLLRAMAIC KLCIGPHASP
     DFASDYLLSP VHAPEALLAQ FPMTYMICGE KDPLVDDTVI FAGRIRQARR KYRQENPLDQ
     TYVRHDGVRV KFLEGISHAF LQMMPFLSEA QQATRTIGDW VKELAHRKQP KVIRRQLSRT
     NTTPLEDHVA QIITTEKDMI HRRKQQLVKG LY
//