ID A0A1C7N3N6_9FUNG Unreviewed; 773 AA.
AC A0A1C7N3N6;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=cysteine--tRNA ligase {ECO:0000256|ARBA:ARBA00012832};
DE EC=6.1.1.16 {ECO:0000256|ARBA:ARBA00012832};
DE AltName: Full=Cysteinyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031499};
GN ORFNames=A0J61_08196 {ECO:0000313|EMBL:OBZ83755.1};
OS Choanephora cucurbitarum.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC Choanephora.
OX NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ83755.1, ECO:0000313|Proteomes:UP000093000};
RN [1] {ECO:0000313|EMBL:OBZ83755.1, ECO:0000313|Proteomes:UP000093000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ83755.1,
RC ECO:0000313|Proteomes:UP000093000};
RA Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT "Choanephora cucurbitarum.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ83755.1}.
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DR EMBL; LUGH01000609; OBZ83755.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7N3N6; -.
DR STRING; 101091.A0A1C7N3N6; -.
DR InParanoid; A0A1C7N3N6; -.
DR OrthoDB; 2140072at2759; -.
DR Proteomes; UP000093000; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004817; F:cysteine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006423; P:cysteinyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00672; CysRS_core; 1.
DR Gene3D; 1.20.120.1910; Cysteine-tRNA ligase, C-terminal anti-codon recognition domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR HAMAP; MF_00041; Cys_tRNA_synth; 1.
DR InterPro; IPR015803; Cys-tRNA-ligase.
DR InterPro; IPR024909; Cys-tRNA/MSH_ligase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR032678; tRNA-synt_1_cat_dom.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR NCBIfam; TIGR00435; cysS; 1.
DR PANTHER; PTHR10890:SF3; CYSTEINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR10890; CYSTEINYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01406; tRNA-synt_1e; 1.
DR PRINTS; PR00983; TRNASYNTHCYS.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OBZ83755.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 41..473
FT /note="tRNA synthetases class I catalytic"
FT /evidence="ECO:0000259|Pfam:PF01406"
FT REGION 725..758
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 682..712
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 773 AA; 87750 MW; 9BD4BE172766CF77 CRC64;
MATENAVKSR QQPKWHVPVQ KTTPVLKFQN SLTKSKNEFI PKDGRRVTWY NCGPTVYDAS
HMGHARTYLS MDIIRRVLED YFRYDVFFVQ NITDIDDKII LRARQQFLFE NLKKETTELS
QPLIQQTEEA WTEFAEAKLK KLDAALVSLA TSNWTEFTQK MTPEEIAKAV ALDEKFKMIY
SALDTSFVAI QHAKASLEKG EKSKEAADLL LVASQDIISS WLDIRKGKEV NDPKVFRDLP
AYWEDKYFQD MQALNVRAPD VQTRVSEYIP EIVDYVQKII DNGYAYVADG SVYFDTSRYD
GHNGHHYAKL EPWSKGDTSL IEDGEGSLGS KLQGKKSPND FALWKASKPG EPVWNSPWSQ
GRPGWHIECS VMASAVVGDN IDIHSGGVDL AFPHHDNELA QAEAYYDCQQ WINYFLHAGH
LHVEGQKMSK SLKNFITINE ALKTYSARQL RLFFLLHQWD AKMDFKKSSM QETIQLEQIM
KNFFDNTKAL VYKVDHDGSR GATELADGGI THRFRENEHA LLSLLQTKQD AVHAALCDSI
NTPVAMNEIM DLIGATNKYM AAQGAKGVNT HLLNKVAKWV TSMMKVFGVA DDGAEIGFGV
TGNGSATTEE ALMPYLRALS SFRDQVRLGA RNKVDHTDFL KLCDSLRDNQ MVDLGVSLDD
QEDGTALVKL VPREELIQIR EKKLAMAAEK EAKKAAAAAE RERKRLEKLE KGKLSPQEMF
KQSDEFSKFD ESGFPTHTKD GEEVTKSRKK KLQKEYDNQK KLHEEYLKEF GSA
//
