ID A0A1C7N608_9FUNG Unreviewed; 658 AA.
AC A0A1C7N608;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Enhancer of polycomb-like protein {ECO:0000256|RuleBase:RU361124};
GN Name=EPL1 {ECO:0000313|EMBL:OBZ84585.1};
GN ORFNames=A0J61_07370 {ECO:0000313|EMBL:OBZ84585.1};
OS Choanephora cucurbitarum.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC Choanephora.
OX NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ84585.1, ECO:0000313|Proteomes:UP000093000};
RN [1] {ECO:0000313|EMBL:OBZ84585.1, ECO:0000313|Proteomes:UP000093000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ84585.1,
RC ECO:0000313|Proteomes:UP000093000};
RA Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT "Choanephora cucurbitarum.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC is involved in transcriptional activation of selected genes principally
CC by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. Involved in gene silencing by neighboring
CC heterochromatin, blockage of the silencing spreading along the
CC chromosome, and required for cell cycle progression through G2/M.
CC {ECO:0000256|ARBA:ARBA00025513}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU361124}.
CC -!- SIMILARITY: Belongs to the enhancer of polycomb family.
CC {ECO:0000256|ARBA:ARBA00008035, ECO:0000256|RuleBase:RU361124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ84585.1}.
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DR EMBL; LUGH01000493; OBZ84585.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7N608; -.
DR STRING; 101091.A0A1C7N608; -.
DR InParanoid; A0A1C7N608; -.
DR OrthoDB; 1343374at2759; -.
DR Proteomes; UP000093000; Unassembled WGS sequence.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR InterPro; IPR024943; Enhancer_polycomb.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR PANTHER; PTHR14898; ENHANCER OF POLYCOMB; 1.
DR PANTHER; PTHR14898:SF0; ENHANCER OF POLYCOMB-LIKE PROTEIN; 1.
DR Pfam; PF10513; EPL1; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU361124};
KW Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU361124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU361124}.
FT DOMAIN 10..157
FT /note="Enhancer of polycomb-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10513"
FT REGION 572..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 73605 MW; 2C349FEF95C3D0AE CRC64;
MPVQMVSRFR VKKLSPKHPL PIYKESQLPD LADTVNQIQR SVPQIETGVE KEEEEEHDLQ
AAISAHQAAV TTGAKVESYI PIPDASNRID TKDYESLYKK KYKEPSTLIR FSSTVEDTIG
CPYFMDEVDE SFLNKFNAEH PTLSEDDFER IMYEFESVTK EKLPHIHLDP DHIPDYTNFM
ELAPESSFLH SRAPVMIEPI FAHWRKRKQD RKGHSIIPDL KYEELMKNEV DPYVCFRRRE
TKPVRKTRRT DQQSLERLRK LRSEMEMARN LLEMVLRREK IRKEGMVLDH TAFDKKCKLR
EYQRILGIKE DEDLLLPSKK KRKTSIGSGA TIKIRLKKDD GRIEKSPAQL AIEADLARKK
QLDAPYEDLT NCSYQPFPAS LPSQFFETAS NGIRYRKRVG RGGRIFIDRA GYQRPISHGG
KTKPGVKLEE SVTKRYQFDF DSNDEDSDIE VDEMQDSYLR HRTQLLSEME LRSLVTIPFL
TPMNMINIQA ARNQAAAAAA VAAAASTNGN NGIASGPSAA SAIAASSQRL SLATGGNAAA
LAAAAAAAAA NSNGNNNNGI ANGLNLADGN RSASPGIAGH PLKRQASRSR MTPQQAAVAM
ANGMIAANMA AAVNGASNPN RTAVQMALAA AQQQQQQQQQ QQQQQQQQQQ QRNTNGIM
//
