ID A0A1C7N9A4_9FUNG Unreviewed; 1030 AA.
AC A0A1C7N9A4;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Calcium permeable stress-gated cation channel 1 {ECO:0000313|EMBL:OBZ85695.1};
GN ORFNames=A0J61_06253 {ECO:0000313|EMBL:OBZ85695.1};
OS Choanephora cucurbitarum.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC Choanephora.
OX NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ85695.1, ECO:0000313|Proteomes:UP000093000};
RN [1] {ECO:0000313|EMBL:OBZ85695.1, ECO:0000313|Proteomes:UP000093000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ85695.1,
RC ECO:0000313|Proteomes:UP000093000};
RA Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT "Choanephora cucurbitarum.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ85695.1}.
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DR EMBL; LUGH01000369; OBZ85695.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7N9A4; -.
DR InParanoid; A0A1C7N9A4; -.
DR OrthoDB; 366603at2759; -.
DR Proteomes; UP000093000; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 49..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 688..708
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 714..733
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..213
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 236..425
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 436..708
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 772..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1030 AA; 117738 MW; 9889E408E3B87097 CRC64;
MEELATTSVN TSTSTVAGFP CIWIFKFLCE DEEPLPGSPA QTSKSPTGFA TQLILCTSVG
FVCFLLFCFL RVRWTTIYSP RLRMRKHAPE ELPATFFGWI IPLLKTPNSV VMEKVGLDAV
VMLQFLLMSV KLFGFCGFFG TVVLYPISRM GGNFANGTLP EQPNNTLYSL SEQHQEFFAT
RLGTNFNAHS VSFLWVYLFF TYLFVFATFY FTFLNYRDYV RIRREFLLRK ARTLSSRTLL
ITGIPPHLRS DRRLADYFEK LGIGVVQSVH LIRHVERLLE FIKERAQHLR QLETAYANYL
GNPVEDPSYD PEEILNYQDA REAQCADGAE LPHFLKSRER PIARQGYIWG SKMDAIDYYT
EQFDEVDELV VKARKVGKFL PTSVGFVTFE ETISAYVASQ VLIDSTPFRL RAQLAPEPRD
VLWENIAMHG RERVIRKFLI MFVLLFLVFS WTIPCNYLSA LTSTKSLKAY FPWLLKLAEK
NKIINQIVAG FIPTLGVVIF FSILPLIFNS LSVIEGFTTR SEAEESCFAK QFFFLFANVL
LFITVTSTLF KSQKDIFEDP IKIANIFASK LPEVAPFYIN YAVLQGIMLC PIQLLQIGPI
IVQQFYRTFL CKTPRDYAEV SAPRMYNFGW GYPVPVFMFV VVLVYSTISP LILVFGVIYF
AMSYLVYKYQ LLYVYFHSYE VAGRMWPLVF TRIIIGLLIF ELTSAGLFTL NKSYPMAALC
LPLVIMTIAY KFMMDRAYQR STQFLPLKLL AEKLGPMKTI ALEGQMLHQQ QQQQQQQQQQ
QQQQQQQSVV SESPTEMTHP PPPAPQAMMP DVHSAESSNN NTMIIRRIRK RRTVLDEDDY
VADPRKFTDF REPPMTLLNG ILNTGMKQYG HPALLGVLPQ LWLPVKAGSE NNRAIMNHST
SVSHSSSFNS FASSTVMADK QQPIIIPKET QPLLLRSEGA AGRSVVNEAD SIVSMPIDDD
VEGGNTDQEE EEDNVGTYYH HPERRLSKNL LSQSYGATSI SSQISNQPVK KKKNKRFLSK
NMRKFSSFFS
//
