ID A0A1C7NFV1_9FUNG Unreviewed; 540 AA.
AC A0A1C7NFV1;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN Name=celI {ECO:0000313|EMBL:OBZ87935.1};
GN ORFNames=A0J61_04012 {ECO:0000313|EMBL:OBZ87935.1};
OS Choanephora cucurbitarum.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC Choanephora.
OX NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ87935.1, ECO:0000313|Proteomes:UP000093000};
RN [1] {ECO:0000313|EMBL:OBZ87935.1, ECO:0000313|Proteomes:UP000093000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ87935.1,
RC ECO:0000313|Proteomes:UP000093000};
RA Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT "Choanephora cucurbitarum.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000966,
CC ECO:0000256|RuleBase:RU361166};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
CC {ECO:0000256|ARBA:ARBA00007072, ECO:0000256|PROSITE-ProRule:PRU10060,
CC ECO:0000256|RuleBase:RU361166}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ87935.1}.
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DR EMBL; LUGH01000187; OBZ87935.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C7NFV1; -.
DR STRING; 101091.A0A1C7NFV1; -.
DR InParanoid; A0A1C7NFV1; -.
DR OrthoDB; 1347382at2759; -.
DR Proteomes; UP000093000; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR001701; Glyco_hydro_9.
DR InterPro; IPR033126; Glyco_hydro_9_Asp/Glu_AS.
DR PANTHER; PTHR22298; ENDO-1,4-BETA-GLUCANASE; 1.
DR PANTHER; PTHR22298:SF29; ENDOGLUCANASE; 1.
DR Pfam; PF00759; Glyco_hydro_9; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00698; GH9_3; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|PROSITE-ProRule:PRU10060};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001,
KW ECO:0000256|RuleBase:RU361166};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PROSITE-
KW ProRule:PRU10060};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU10060}; Membrane {ECO:0000256|SAM:Phobius};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|PROSITE-ProRule:PRU10060};
KW Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW Signal {ECO:0000256|RuleBase:RU361166};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|RuleBase:RU361166"
FT CHAIN 23..540
FT /note="Endoglucanase"
FT /evidence="ECO:0000256|RuleBase:RU361166"
FT /id="PRO_5008810994"
FT TRANSMEM 505..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..475
FT /note="Glycoside hydrolase family 9"
FT /evidence="ECO:0000259|Pfam:PF00759"
FT ACT_SITE 454
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
FT ACT_SITE 463
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
SQ SEQUENCE 540 AA; 59303 MW; 3E04CDD3AE677862 CRC64;
MRLSIIYQSI ALVGSLTQCV FAVEQPTTDG PSNPPGVTGN VHYANLLNAS MWFYEAQRSG
YLPSNNRVPW RSNSALQDGS DNNVNLTGGY YDAGDYLKFS LPLAYSLSSI AWSASAWFDG
YQKANQVGYL ADTIKWGTDW LIKAHPNNDT FYVQVGDGDI DNNYWGPDTN IPTPRPSYQV
NRTVVGTDAV AISAAALASA SYLFRNHIND TDYADTLLTS AISLFNLADT AQPRNVYTRS
LPQLAAYYNT NNYTSQLTYA ALWMYKATKN ETYRTMASDY FDQFKLGSSQ ISVMDWSDQT
NGVFVLGAEQ DPNNSKYATA AKKVLDAITT GGTGSPCSFT SGGLLWCDGY STENSLIPAQ
DMALLALLYS RLDSSKSDGY TQFAQKQIDY LLGKNYMNTP YVCGIHKNSP RNPHHAGASG
GTDIGNINSS PAEETYILYG AIVGGPDNND KFYDVRNDYA QTEVALDYNA PFQGLVAYQM
STGAADPPYV TITEDRPNVS RSSGLPGWVI AVIVVCIVFV IALVSYIIWW KRCCCFKNRS
//
