ID   A0A1C7NHV5_9FUNG        Unreviewed;       595 AA.
AC   A0A1C7NHV5;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Enhancer of polycomb-like protein {ECO:0000256|RuleBase:RU361124};
GN   Name=epl1 {ECO:0000313|EMBL:OBZ86914.1};
GN   ORFNames=A0J61_05032 {ECO:0000313|EMBL:OBZ86914.1};
OS   Choanephora cucurbitarum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC   Choanephora.
OX   NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ86914.1, ECO:0000313|Proteomes:UP000093000};
RN   [1] {ECO:0000313|EMBL:OBZ86914.1, ECO:0000313|Proteomes:UP000093000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ86914.1,
RC   ECO:0000313|Proteomes:UP000093000};
RA   Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT   "Choanephora cucurbitarum.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC       is involved in transcriptional activation of selected genes principally
CC       by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC       also involved in DNA repair. Involved in gene silencing by neighboring
CC       heterochromatin, blockage of the silencing spreading along the
CC       chromosome, and required for cell cycle progression through G2/M.
CC       {ECO:0000256|ARBA:ARBA00025513}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU361124}.
CC   -!- SIMILARITY: Belongs to the enhancer of polycomb family.
CC       {ECO:0000256|ARBA:ARBA00008035, ECO:0000256|RuleBase:RU361124}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBZ86914.1}.
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DR   EMBL; LUGH01000261; OBZ86914.1; -; Genomic_DNA.
DR   STRING; 101091.A0A1C7NHV5; -.
DR   InParanoid; A0A1C7NHV5; -.
DR   OrthoDB; 1343374at2759; -.
DR   Proteomes; UP000093000; Unassembled WGS sequence.
DR   GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR024943; Enhancer_polycomb.
DR   InterPro; IPR019542; Enhancer_polycomb-like_N.
DR   PANTHER; PTHR14898; ENHANCER OF POLYCOMB; 1.
DR   PANTHER; PTHR14898:SF0; ENHANCER OF POLYCOMB-LIKE PROTEIN; 1.
DR   Pfam; PF10513; EPL1; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU361124};
KW   Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU361124};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU361124}.
FT   DOMAIN          10..157
FT                   /note="Enhancer of polycomb-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10513"
FT   REGION          423..443
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   595 AA;  68004 MW;  B6497DBF9207E432 CRC64;
     MVNQMVSRFR VKKLSPKHPL PVYKEYQLPX LSDAANIQRA VPQIETGVEK EEEEEHDLQA
     AISAAQAAVT TGANIEKYIP IPDASRLISN EEYTTLYKKN HKDPSTLIRF SSTVEDCIGC
     PYLMDEEDDN FLKDYNKQHP GEILSEDLFE NIMWELESIT NQQWPHLALD PQIPEYKVFL
     EHVPGYSKLK SIPNLPAIYA HWSKRRQKRE GKSVTPCLKF EEAYKNEMDP YVCFRRRETK
     PARKTRRSDQ QSLERLRKLR LEMEMARNLL ERVLRREKIR KECLVVEHAV FEKRCALYEY
     QRILGIKEDE DLLLPKKKQR TSSEGSSTTI KIPLHKLKST IRFDKSPTQI AIEAELSRKR
     EADALYEDVT EFGYQPFALT TPQLFYQQLS VSGKTKPAGP KFRKRMGRNG RLFIDRVGFS
     LKPSSGGKSK PGAPLYDLSR FDSDMSDSED NEIEIDEMDS MFLKHRAQLL TETELRNLVT
     VPFLTPNNIM NMNQVRYAAA AFNNSDNRTP QTLTIQQQQP KQQSAALMNG TAVPLKRQNS
     GRTKMTPQQA SVAMASGMIA ANMTAAVHNT SNTGKTAIQM AMAAAQHQQQ LSNGK
//