ID   A0A1C7NPQ0_9FUNG        Unreviewed;       392 AA.
AC   A0A1C7NPQ0;
DT   30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Delta(12) fatty acid desaturase {ECO:0000313|EMBL:OBZ91101.1};
GN   Name=FAD12 {ECO:0000313|EMBL:OBZ91101.1};
GN   ORFNames=A0J61_00857 {ECO:0000313|EMBL:OBZ91101.1};
OS   Choanephora cucurbitarum.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Choanephoraceae; Choanephoroideae;
OC   Choanephora.
OX   NCBI_TaxID=101091 {ECO:0000313|EMBL:OBZ91101.1, ECO:0000313|Proteomes:UP000093000};
RN   [1] {ECO:0000313|EMBL:OBZ91101.1, ECO:0000313|Proteomes:UP000093000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KUS-F28377 {ECO:0000313|EMBL:OBZ91101.1,
RC   ECO:0000313|Proteomes:UP000093000};
RA   Min B., Park H., Park J.-H., Shin H.-D., Choi I.-G.;
RT   "Choanephora cucurbitarum.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC   -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00009295}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBZ91101.1}.
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DR   EMBL; LUGH01000022; OBZ91101.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1C7NPQ0; -.
DR   STRING; 101091.A0A1C7NPQ0; -.
DR   InParanoid; A0A1C7NPQ0; -.
DR   OrthoDB; 4215at2759; -.
DR   Proteomes; UP000093000; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProt.
DR   CDD; cd03507; Delta12-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR   PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000093000};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        59..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        235..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        269..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          88..360
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   392 AA;  45304 MW;  91618DEB3AFDA3B7 CRC64;
     MATQRNVKSD SAAQNAVKPV IDEAIERNWE IPEFTIKEIR DAIPAHCFRR DTFTSFTHVL
     HDFAIVGFLA YLASYIDTIP NVYARIALWP MYWIAQGIVG TGVWVLGHEC GHQAFSPSKT
     INNSVGFVLH TLLLVPYHSW RFSHSRHHKA TGHMSKDQVF LPKTRNKIGL PARDQDPQAD
     GPHDVLEETP IASLWRMFLM FTFGWPLYLF TNVTGQDYPG WASHFNPTCD IYEEGQYWDV
     MTSTAGIIAM IGFLTYCGQI FGSLTMIKFY VIPYLNVNFW LVLITYLQHT DPKLPHYREN
     VWNFQRGAAL TVDRSYGAII NYFHHHISDT HVAHHFFSTM PFYHAQEATL HIKKALGKHY
     NCDNTPIPIA LWRVWKECRF VEDEGDVVFY KK
//