ID A0A1C9WQ69_9MICC Unreviewed; 679 AA.
AC A0A1C9WQ69;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=protein-N(pi)-phosphohistidine--D-fructose phosphotransferase {ECO:0000256|ARBA:ARBA00012799};
DE EC=2.7.1.202 {ECO:0000256|ARBA:ARBA00012799};
GN ORFNames=ASPU41_07260 {ECO:0000313|EMBL:AOT03168.1};
OS Arthrobacter sp. U41.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1849032 {ECO:0000313|EMBL:AOT03168.1, ECO:0000313|Proteomes:UP000095776};
RN [1] {ECO:0000313|EMBL:AOT03168.1, ECO:0000313|Proteomes:UP000095776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U41 {ECO:0000313|EMBL:AOT03168.1,
RC ECO:0000313|Proteomes:UP000095776};
RA Fomenkov A., Akimov V.N., Vasilyeva L.V., Andersen D., Vincze T.,
RA Roberts R.J.;
RT "Complete Genome and Methylome Analysis of Psychrotrophic Bacterial
RT Isolates from Antarctic Lake Untersee.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-
CC fructose 1-phosphate(in) + L-histidyl-[protein];
CC Xref=Rhea:RHEA:49252, Rhea:RHEA-COMP:9745, Rhea:RHEA-COMP:9746,
CC ChEBI:CHEBI:29979, ChEBI:CHEBI:37721, ChEBI:CHEBI:58674,
CC ChEBI:CHEBI:64837; EC=2.7.1.202;
CC Evidence={ECO:0000256|ARBA:ARBA00001401};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP015732; AOT03168.1; -; Genomic_DNA.
DR RefSeq; WP_069950354.1; NZ_CP015732.1.
DR AlphaFoldDB; A0A1C9WQ69; -.
DR STRING; 1849032.ASPU41_07260; -.
DR KEGG; aru:ASPU41_07260; -.
DR OrthoDB; 9782569at2; -.
DR Proteomes; UP000095776; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR GO; GO:0022877; F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR CDD; cd00211; PTS_IIA_fru; 1.
DR CDD; cd05569; PTS_IIB_fructose; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR013011; PTS_EIIB_2.
DR InterPro; IPR003501; PTS_EIIB_2/3.
DR InterPro; IPR013014; PTS_EIIC_2.
DR InterPro; IPR004715; PTS_IIA_fruc.
DR InterPro; IPR003353; PTS_IIB_fruc.
DR InterPro; IPR006327; PTS_IIC_fruc.
DR NCBIfam; TIGR00829; FRU; 1.
DR NCBIfam; TIGR00848; fruA; 1.
DR NCBIfam; TIGR01427; PTS_IIC_fructo; 1.
DR PANTHER; PTHR30505; FRUCTOSE-LIKE PERMEASE; 1.
DR PANTHER; PTHR30505:SF0; FRUCTOSE-LIKE PTS SYSTEM EIIBC COMPONENT-RELATED; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR Pfam; PF02302; PTS_IIB; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS51099; PTS_EIIB_TYPE_2; 1.
DR PROSITE; PS51104; PTS_EIIC_TYPE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000095776};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 323..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..147
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
FT DOMAIN 186..281
FT /note="PTS EIIB type-2"
FT /evidence="ECO:0000259|PROSITE:PS51099"
FT DOMAIN 315..670
FT /note="PTS EIIC type-2"
FT /evidence="ECO:0000259|PROSITE:PS51104"
SQ SEQUENCE 679 AA; 68960 MW; 71E3C382BA8040B1 CRC64;
MTQLITTDLV ELDQNLGSSP EDVIRHLAGK VAANGRATEV EGLFADAFAR EQKTATGVPG
GIAIPHCRST AVTEPTLVMA RLSQPVDFGA KDGPADLIFF IAAPEGADQD HLKLLSRLAR
SLIKKDFTAS LRAAGSEAEV VELVEGALAD KPAAAAGAAA PAAAAAGAAA SSAAPETAGA
ARPKRLVAVT ACPTGIAHTY MAADSLVAAA KEVGVDLQVE TQGSSGAKPL DPAVIAAADA
VIFAVDVDVR GKERFAGKPV INAPVKRGID EPGKMVQEAL AAADNPNARR VPHFGAEEQA
QHEAEEKGEH IGQKLKRALL TGVSYMIPFV AGGGLLIALG FLLGGYDITD VADKVVVENN
FGNLPEGGLA IYLGAVLFKI GALSMGFLVP ALAGYIAYAI ADRPGIAPGF VAGAVAGFMG
AGFLGGIVGG LLAGYMAHLI GTWQVPRWLR GLMPVVIIPL LASIFASGLM FLVLGGPIAG
LTKALNEWLS GMTGASAVVL GIILGLMMCF DLGGPVNKVA YAFAVAGLSA GSATNQAPWQ
IMAAVMAAGM VPPLAMALAT VLDKKLFSLA ERENGKAAWL LGASFISEGA IPFAAADPLR
VIPASMVGGA LTGALCMATG VTSQAPHGGI FVFFAIGNLV MFVVAILAGT VVSALAVVAL
KRWAAKKTVD TVEPVPVAA
//
